| For: | Lin CP, Liu CR, Lee CN, Chan TS, Liu HE. Targeting c-Myc as a novel approach for hepatocellular carcinoma. World J Hepatol 2010; 2(1): 16-20 [PMID: 21160952 DOI: 10.4254/wjh.v2.i1.16] |
|---|---|
| URL: | https://www.wjgnet.com/1948-5182/full/v2/i1/16.htm |
| Number | Citing Articles |
| 1 |
Lorena González, Johanna G Miquet, Pablo E Irene, M Eugenia Díaz, Soledad P Rossi, Ana I Sotelo, Mónica B Frungieri, Cristal M Hill, Andrzej Bartke, Daniel Turyn. Attenuation of epidermal growth factor (EGF) signaling by growth hormone (GH). Journal of Endocrinology 2017; 233(2) doi: 10.1530/JOE-16-0606
|
| 2 |
Yongsheng Huang, Meng Nie, Chuang Li, Yingjie Zhao, Jiahui Li, Lan Zhou, Lin Wang. RLIM suppresses hepatocellular carcinogenesis by up-regulating p15 and p21. Oncotarget 2017; 8(47) doi: 10.18632/oncotarget.20904
|
| 3 |
Celia Sequera, Margherita Grattarola, Agnes Holczbauer, Rosanna Dono, Stefania Pizzimenti, Giuseppina Barrera, Kirk J. Wangensteen, Flavio Maina. MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities. Cell Death & Disease 2022; 13(11) doi: 10.1038/s41419-022-05411-6
|
| 4 |
Mario Di Matteo, Emira Samara-Kuko, Natalie J Ward, Simon N Waddingon, John H McVey, Marinee KL Chuah, Thierry VandenDriessche. Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy. Molecular Therapy 2014; 22(9) doi: 10.1038/mt.2014.131
|
| 5 |
Ning Bu, Shurui Wang, Yupeng Ma, Haibo Xia, Yuhang Zhao, Xuemin Shi, Qizhan Liu, Suhua Wang, Yanrong Gao. The lncRNA H19/miR-29a-3p/SNIP1/c-myc regulatory axis is involved in pulmonary fibrosis induced by Nd2O3. Toxicological Sciences 2024; 197(1) doi: 10.1093/toxsci/kfad107
|
| 6 |
Chia‐Jui Yen, Yu‐Lin Ai, Hung‐Wen Tsai, Shih‐Huang Chan, Chia‐Sheng Yen, Kuang‐Hsiung Cheng, Yun‐Ping Lee, Chia‐Wei Kao, Yu‐Chun Wang, Yi‐Lin Chen, Cheng‐Han Lin, Tsunglin Liu, Huey‐Pin Tsai, Jen‐Ren Wang, Ih‐Jen Su, Wenya Huang. Hepatitis B virus surface gene pre‐S2 mutant as a high‐risk serum marker for hepatoma recurrence after curative hepatic resection. Hepatology 2018; 68(3) doi: 10.1002/hep.29790
|
| 7 |
William Senapedis, Kayleigh M. Gallagher, Elmer Figueroa, Jeremiah D. Farelli, Robert Lyng, J. Graeme Hodgson, Charles W. O’Donnell, Joseph V. Newman, Madison Pacaro, Stephen K. Siecinski, Justin Chen, Thomas G. McCauley. Targeted transcriptional downregulation of MYC using epigenomic controllers demonstrates antitumor activity in hepatocellular carcinoma models. Nature Communications 2024; 15(1) doi: 10.1038/s41467-024-52202-y
|
| 8 |
Luowei Yuan, Yikai Xiong, Yiming Zhang, Shen Gu, Yong Lei. Epigenome editing based treatment: Progresses and challenges. Molecular Therapy 2026; 34(1) doi: 10.1016/j.ymthe.2025.08.047
|
| 9 |
Parul Suri, Abel B. Daartey, D.M. Isha Olive Khan, Naga Pradeep Rayana, Rameswari Chilamakuri, Deepika Godugu, Mahan Gholam Azad, Katelyn L. Reeb, Des R. Richardson. Harnessing autophagy and its transcriptional regulation in tumorigenesis and neurodegeneration: Potential and existing therapeutic strategies. Pharmacological Reviews 2026; doi: 10.1016/j.pharmr.2026.100158
|
| 10 |
Zhangwei Tong, Ming Li, Wei Wang, Pingli Mo, Li Yu, Kun Liu, Wenjing Ren, Wengang Li, Hao Zhang, Jianming Xu, Chundong Yu. Steroid Receptor Coactivator 1 Promotes Human Hepatocellular Carcinoma Progression by Enhancing Wnt/β-Catenin Signaling. Journal of Biological Chemistry 2015; 290(30) doi: 10.1074/jbc.M115.640490
|
| 11 |
Rajni Kant, Ming-Hui Yang, Chih-Hua Tseng, Chia-Hung Yen, Wei-You Li, Yu-Chang Tyan, Marcelo Chen, Cherng-Chyi Tzeng, Wei-Cheng Chen, Kaiting You, Wen-Chieh Wang, Yeh-Long Chen, Yi-Ming Arthur Chen. Discovery of an Orally Efficacious MYC Inhibitor for Liver Cancer Using a GNMT-Based High-Throughput Screening System and Structure–Activity Relationship Analysis. Journal of Medicinal Chemistry 2021; 64(13) doi: 10.1021/acs.jmedchem.1c00093
|
| 12 |
Terezinha M Souza, Linda Rieswijk, Twan van den Beucken, Jos Kleinjans, Danyel Jennen. Persistent transcriptional responses show the involvement of feed-forward control in a repeated dose toxicity study. Toxicology 2017; 375 doi: 10.1016/j.tox.2016.10.009
|
| 13 |
Johanna G. Miquet, Thomas Freund, Carolina S. Martinez, Lorena González, María E. Díaz, Giannina P. Micucci, Elsa Zotta, Ravneet K. Boparai, Andrzej Bartke, Daniel Turyn, Ana I. Sotelo. Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone. Cell Cycle 2013; 12(7) doi: 10.4161/cc.24026
|
| 14 |
María E Díaz, Johanna G Miquet, Soledad P Rossi, Pablo E Irene, Ana I Sotelo, Mónica B Frungieri, Daniel Turyn, Lorena González. GH administration patterns differently regulate epidermal growth factor signaling. Journal of Endocrinology 2014; 221(2) doi: 10.1530/JOE-13-0447
|
| 15 |
Mona Malz, Federico Pinna, Peter Schirmacher, Kai Breuhahn. Transcriptional regulators in hepatocarcinogenesis – Key integrators of malignant transformation. Journal of Hepatology 2012; 57(1) doi: 10.1016/j.jhep.2011.11.029
|
| 16 |
Krishnapriya Ramakrishnan, Riya Vishwakarma, Radul R. Dev, Rajesh Raju, Niyas Rehman. Etiologically Significant microRNAs in Hepatitis B Virus-Induced Hepatocellular Carcinoma. OMICS: A Journal of Integrative Biology 2024; 28(6) doi: 10.1089/omi.2024.0071
|
| 17 |
Rhys Gillman, Eun Jin Sun, Miriam Wankell, Matt A. Field, Ulf Schmitz, Lionel Hebbard. Molecular characterization of the A52 murine hepatocellular carcinoma cell line. Animal Models and Experimental Medicine 2026; 9(3) doi: 10.1002/ame2.70152
|
| 18 |
Wai Yeow Lee, Maulana Bachtiar, Cheryl C. S. Choo, Caroline G. Lee. Comprehensive review of Hepatitis B Virus‐associated hepatocellular carcinoma research through text mining and big data analytics. Biological Reviews 2019; 94(2) doi: 10.1111/brv.12457
|
| 19 |
Francesca Balzano, Giuseppe Garroni, Sara Cruciani, Emanuela Bellu, Silvia Dei Giudici, Annalisa Oggiano, Giampiero Capobianco, Salvatore Dessole, Carlo Ventura, Margherita Maioli. Behavioral Changes in Stem-Cell Potency by HepG2-Exhausted Medium. Cells 2020; 9(8) doi: 10.3390/cells9081890
|
| 20 |
Cheng He, Chuanyu Tang, Jie Guo, Xiangyi Yin, Qing Zhu, Chihua Fang. CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability. Journal of Translational Medicine 2025; 23(1) doi: 10.1186/s12967-025-06983-5
|
| 21 |
Xin Huang, Weiyue Zhang, Zengwu Shao. Association between long non-coding RNA polymorphisms and cancer risk: a meta-analysis. Bioscience Reports 2018; 38(4) doi: 10.1042/BSR20180365
|
| 22 |
Na Shang, Hao Wang, Thomas Bank, Aldeb Perera, Cara Joyce, Gina Kuffel, Michael J. Zilliox, Scott J. Cotler, Xianzhong Ding, Asha Dhanarajan, Peter Breslin, Wei Qiu. Focal Adhesion Kinase and β‐Catenin Cooperate to Induce Hepatocellular Carcinoma. Hepatology 2019; 70(5) doi: 10.1002/hep.30707
|
| 23 |
Shakeel Ahmad Khan, Huihai Yang, Fan Ying, Chin Ngok Chu, Terence Kin Wah Lee. Polypharmacology‐Driven Discovery of ZAK‐I‐57: A Potent Multi‐Targeted Benzoxazinone Small Molecule for Hepatocellular Carcinoma Therapy. MedComm 2025; 6(8) doi: 10.1002/mco2.70291
|
| 24 |
Katarzyna Urbanek-Olejnik, Monika Liszewska, Alicja Winczura, Grażyna Kostka. Changes of c-Myc and DNMT1 mRNA and protein levels in the rat livers induced by dibutyl phthalate treatment. Toxicology and Industrial Health 2016; 32(5) doi: 10.1177/0748233713512363
|
| 25 |
Lynn YL Huang, Chia-chi Chang, Ying-Shuan Lee, Jiann-Jyh Huang, Shih-Hsien Chuang, Jia-Ming Chang, Kuo-Jang Kao, Gillian MG Lau, Pei-Yi Tsai, Chia-wei Liu, Her-Sheng Lin, Robert G. Gish, Johnson YN Lau. Inhibition of Hec1 as a novel approach for treatment of primary liver cancer. Cancer Chemotherapy and Pharmacology 2014; 74(3) doi: 10.1007/s00280-014-2540-7
|
| 26 |
Yubo Jiang, Qian Cheng, Yingying Zhang, Jingtao Zhong. PUS7 promotes the progression of pancreatic cancer by interacting ANLN to activate MYC pathway. Molecular and Cellular Biochemistry 2025; 480(7) doi: 10.1007/s11010-025-05267-2
|
| 27 |
Ulfa Kholili, Alvin Hartanto Kurniawan, Choirina Winda, Ummi Maimunah, Poernomo Budi Setiawan. The Role of Metformin as Chemopreventive Strategies for Hepatocellular Carcinoma. Research Journal of Pharmacy and Technology 2023; doi: 10.52711/0974-360X.2023.00065
|
| 28 |
Danele Hunecke, Reinhard Spanel, Florian Länger, Suk Woo Nam, Juergen Borlak. MYC‐regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer. The Journal of Pathology 2012; 228(4) doi: 10.1002/path.4059
|
| 29 |
Shuang Fu, Yan Guo, Hong Chen, Zhen-Ming Xu, Guang-Bin Qiu, Ming Zhong, Kai-Lai Sun, Wei-Neng Fu, Klaus Roemer. MYCT1-TV, A Novel MYCT1 Transcript, Is Regulated by c-Myc and May Participate in Laryngeal Carcinogenesis. PLoS ONE 2011; 6(10) doi: 10.1371/journal.pone.0025648
|
| 30 |
Yalei Yin, Mingju Sun, Xi Zhan, Changqing Wu, Pengyu Geng, Xiaoyan Sun, Yunsong Wu, Shuijun Zhang, Jianhua Qin, Zhengping Zhuang, Yang Liu. EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC. Journal of Experimental & Clinical Cancer Research 2019; 38(1) doi: 10.1186/s13046-019-1082-6
|
| 31 |
Brittany Anderton, Roman Camarda, Sanjeev Balakrishnan, Asha Balakrishnan, Rebecca A Kohnz, Lionel Lim, Kimberley J Evason, Olga Momcilovic, Klaus Kruttwig, Qiang Huang, Guowang Xu, Daniel K Nomura, Andrei Goga. MYC‐driven inhibition of the glutamate‐cysteine ligase promotes glutathione depletion in liver cancer. The EMBO Reports 2017; 18(4) doi: 10.15252/embr.201643068
|
| 32 |
Aishwarya Saraswat, Hari Priya Vemana, Vikas V. Dukhande, Ketan Patel. Galactose-decorated liver tumor-specific nanoliposomes incorporating selective BRD4-targeted PROTAC for hepatocellular carcinoma therapy. Heliyon 2022; 8(1) doi: 10.1016/j.heliyon.2021.e08702
|
| 33 |
Vaibhav Rastogi, Pragya Yadav, Shiv Sankar Bhattacharya, Arun Kumar Mishra, Navneet Verma, Anurag Verma, Jayanta Kumar Pandit. Carbon Nanotubes: An Emerging Drug Carrier for Targeting Cancer Cells. Journal of Drug Delivery 2014; 2014 doi: 10.1155/2014/670815
|
| 34 |
Xuefeng Wang, Yanru Tang, Rui Liu, Wentao Li, Shiyue Liu, Xinhong Zhou.
Pan-cancer analysis of
BRK1
as a potential immunotherapeutic target
. Biotechnology and Genetic Engineering Reviews 2024; 40(3) doi: 10.1080/02648725.2023.2196179
|
| 35 |
Kurt Sartorius, Ping An, Cheryl Winkler, Anil Chuturgoon, Xiaodong Li, Julia Makarova, Anna Kramvis. The Epigenetic Modulation of Cancer and Immune Pathways in Hepatitis B Virus-Associated Hepatocellular Carcinoma: The Influence of HBx and miRNA Dysregulation. Frontiers in Immunology 2021; 12 doi: 10.3389/fimmu.2021.661204
|
| 36 |
Muntadher Jihad, İdil Yet. Multiomics Integration at Single-Cell Resolution Using Bayesian Networks: A Case Study in Hepatocellular Carcinoma. OMICS: A Journal of Integrative Biology 2023; 27(1) doi: 10.1089/omi.2022.0170
|
| 37 |
Marwa M. Abu-Serie, Ashraf A. El-Faham, Ghada M. Ahmad, Noha H. Habashy. Unsaponifiable fraction of black Vitis vinifera seed oil attenuates liver cancer progression by targeting apoptosis and key tumor-associated genes: In vitro, in vivo, and in silico studies. Scientific Reports 2026; 16(1) doi: 10.1038/s41598-026-44404-9
|
| 38 |
Nirali Pandya, Eshan Khan, Neha Jain, Lakshminarayana Satham, Rahul Singh, Ravindra D. Makde, Amit Mishra, Amit Kumar. Curcumin analogs exhibit anti-cancer activity by selectively targeting G-quadruplex forming c-myc promoter sequence. Biochimie 2021; 180 doi: 10.1016/j.biochi.2020.11.006
|
| 39 |
Libo Sun, Hansheng Zhou, Xiaofei Zhao, Haitao Zhang, Yan Wang, Guangming Li. Small RNA sequencing identified miR-3180 as a potential prognostic biomarker for Chinese hepatocellular carcinoma patients. Frontiers in Genetics 2023; 14 doi: 10.3389/fgene.2023.1102171
|
| 40 |
XING-XING HE, AN-YUAN GUO, CHUAN-RUI XU, YING CHANG, GUANG-YA XIANG, JING GONG, ZI-LI DAN, DE-AN TIAN, JIA-ZHI LIAO, JU-SHENG LIN. Bioinformatics analysis identifies miR-221 as a core regulator in hepatocellular carcinoma and its silencing suppresses tumor properties. Oncology Reports 2014; 32(3) doi: 10.3892/or.2014.3306
|
| 41 |
Jia-Yuan Huang, Kai Zhang, Dong-Qin Chen, Jing Chen, Bing Feng, Haizhu Song, Yitian Chen, Ziman Zhu, Lei Lu, Wei De, Rui Wang, Long-Bang Chen. MicroRNA-451: epithelial-mesenchymal transition inhibitor and prognostic biomarker of hepatocelluar carcinoma. Oncotarget 2015; 6(21) doi: 10.18632/oncotarget.4317
|
| 42 |
Rushabh Gujarathi, Joseph W. Franses, Anjana Pillai, Chih-Yi Liao. Targeted therapies in hepatocellular carcinoma: past, present, and future. Frontiers in Oncology 2024; 14 doi: 10.3389/fonc.2024.1432423
|
| 43 |
Kang Zheng, Francisco Cubero, Yulia Nevzorova. c-MYC—Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease. Genes 2017; 8(4) doi: 10.3390/genes8040123
|
| 44 |
Wona Jee, Hyun Min Ko, Do-Il Park, Ye-Rin Park, So-Mi Park, Hyungsuk Kim, Yun-Cheol Na, Ji Hoon Jung, Hyeung-Jin Jang. Momordicae Semen inhibits migration and induces apoptotic cell death by regulating c-Myc and CNOT2 in human pancreatic cancer cells. Scientific Reports 2023; 13(1) doi: 10.1038/s41598-023-39840-w
|
| 45 |
Katja Hueper, Mahmoud Elalfy, Florian Laenger, Roman Halter, Thomas Rodt, Michael Galanski, Juergen Borlak, Martin W. Brechbiel. PET/CT Imaging of c-Myc Transgenic Mice Identifies the Genotoxic N-Nitroso-Diethylamine as Carcinogen in a Short-Term Cancer Bioassay. PLoS ONE 2012; 7(2) doi: 10.1371/journal.pone.0030432
|
| 46 |
Rajagopal N Aravalli, Neil C Talbot, Clifford J Steer. Gene expression profiling of MYC-driven tumor signatures in porcine liver stem cells by transcriptome sequencing. World Journal of Gastroenterology 2015; 21(7): 2011-2029 doi: 10.3748/wjg.v21.i7.2011
|
| 47 |
Manasi Kotulkar, Diego Paine-Cabrera, Sarah Abernathy, Dakota R. Robarts, Wendena S. Parkes, Kristi Lin-Rahardja, September Numata, Margitta Lebofsky, Hartmut Jaeschke, Udayan Apte. Role of HNF4alpha-cMyc interaction in liver regeneration and recovery after acetaminophen-induced acute liver injury. Hepatology 2023; 78(4) doi: 10.1097/HEP.0000000000000367
|
| 48 |
Junzhi Li, Jing Chu, Vincent Chi Hang Lui, Shangsi Chen, Yan Chen, Paul Kwong Hang Tam. Bioengineering Liver Organoids for Diseases Modelling and Transplantation. Bioengineering 2022; 9(12) doi: 10.3390/bioengineering9120796
|
| 49 |
Wu-Lung R. Yang, Yu-En Lee, Ming-Huang Chen, Kun-Mao Chao, Chi-Ying F. Huang. In-silico drug screening and potential target identification for hepatocellular carcinoma using Support Vector Machines based on drug screening result. Gene 2013; 518(1) doi: 10.1016/j.gene.2012.11.030
|
| 50 |
Yan Zhao, Wang Jian, Wei Gao, Ya-Xin Zheng, Yong-Kun Wang, Zhu-Qing Zhou, Hui Zhang, Cong-Jun Wang. RNAi silencing of c-Myc inhibits cell migration, invasion, and proliferation in HepG2 human hepatocellular carcinoma cell line: c-Myc silencing in hepatocellular carcinoma cell. Cancer Cell International 2013; 13(1) doi: 10.1186/1475-2867-13-23
|
| 51 |
A. Bhatt, A. Jain, E. Gurnany, R. Jain, A. Modi, A. Jain. Nanoarchitectonics for Smart Delivery and Drug Targeting. 2016; doi: 10.1016/B978-0-323-47347-7.00017-3
|
| 52 |
DRAZEN B. ZIMONJIC, NICHOLAS C. POPESCU. Role of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: Potential prospects for combined targeted therapeutics. International Journal of Oncology 2012; 41(2) doi: 10.3892/ijo.2012.1474
|
| 53 |
Chuan Yan, Qiqi Yang, Xiaojing Huo, Hankun Li, Li Zhou, Zhiyuan Gong. RETRACTED ARTICLE: Chemical inhibition reveals differential requirements of signaling pathways in krasV12- and Myc-induced liver tumors in transgenic zebrafish. Scientific Reports 2017; 7(1) doi: 10.1038/srep45796
|
| 54 |
Asaad Azarnezhad, Parvin Mehdipour. Cancer Genetics and Psychotherapy. 2017; doi: 10.1007/978-3-319-64550-6_5
|
| 55 |
SM Nashir Udden, Youn-Tae Kwak, Victoria Godfrey, Md Abdul Wadud Khan, Shahanshah Khan, Nicolas Loof, Lan Peng, Hao Zhu, Hasan Zaki. NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte. eLife 2019; 8 doi: 10.7554/eLife.40396
|
| 56 |
Shanthi Ganesh, Xue Shui, Kevin P. Craig, Martin L. Koser, Girish R. Chopda, Wendy A. Cyr, Chengjung Lai, Henryk Dudek, Weimin Wang, Bob D. Brown, Marc T. Abrams. β-Catenin mRNA Silencing and MEK Inhibition Display Synergistic Efficacy in Preclinical Tumor Models. Molecular Cancer Therapeutics 2018; 17(2) doi: 10.1158/1535-7163.MCT-17-0605
|
| 57 |
Zheng Chen, Zengliang Li, Wei Li, Yang Zong, Yi Zhu, Yi Miao, Zekuan Xu. SATB1 Promotes Pancreatic Cancer Growth and Invasion Depending on MYC Activation. Digestive Diseases and Sciences 2015; 60(11) doi: 10.1007/s10620-015-3759-9
|
| 58 |
Huiqing Li, Chunying Wei. Mechanism studies on anti-HepG2 cell proliferation of phenanthroline derivatives as G-quadruplex DNA stabilizers. Bioorganic & Medicinal Chemistry Letters 2015; 25(18) doi: 10.1016/j.bmcl.2015.07.085
|
| 59 |
Kevin Berendse, Bart G. P. Koot, Femke C. C. Klouwer, Marc Engelen, Frank Roels, Miangela M. Lacle, Peter G. J. Nikkels, Joanne Verheij, Bwee Tien Poll‐The. Hepatic symptoms and histology in 13 patients with a Zellweger spectrum disorder. Journal of Inherited Metabolic Disease 2019; 42(5) doi: 10.1002/jimd.12132
|
| 60 |
Wei Fan, Heping Yang, Ting Liu, Jiaohong Wang, Tony W.H. Li, Nirmala Mavila, Yuanyuan Tang, JinWon Yang, Hui Peng, Jian Tu, Alagappan Annamalai, Mazen Noureddin, Anuradha Krishnan, Gregory J. Gores, Maria L. Martínez‐Chantar, José M. Mato, Shelly C. Lu. Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells. Hepatology 2017; 65(4) doi: 10.1002/hep.28964
|
| 61 |
Rajni Kant, Chia-Hung Yen, Jung-Hsien Hung, Chung-Kuang Lu, Chien-Yi Tung, Pei-Ching Chang, Yueh-Hao Chen, Yu-Chang Tyan, Yi-Ming Arthur Chen. Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-018-37292-1
|
| 62 |
Tomoyuki Honda, Md. Arifur Rahman. Profiling of LINE-1-Related Genes in Hepatocellular Carcinoma. International Journal of Molecular Sciences 2019; 20(3) doi: 10.3390/ijms20030645
|
| 63 |
Rania Hassan Mohamed, Nourhan Abu-Shahba, Marwa Mahmoud, Ahmed M. H. Abdelfattah, Wael Zakaria, Mahmoud ElHefnawi. Co-regulatory Network of Oncosuppressor miRNAs and Transcription Factors for Pathology of Human Hepatic Cancer Stem Cells (HCSC). Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-41978-5
|
| 64 |
Abel Sousa, Aurelien Dugourd, Danish Memon, Borgthor Petursson, Evangelia Petsalaki, Julio Saez‐Rodriguez, Pedro Beltrao. Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival. Molecular Systems Biology 2023; 19(3) doi: 10.15252/msb.202110631
|
| 65 |
Michele Signore, Lucia Ricci-Vitiani, Ruggero De Maria. Targeting apoptosis pathways in cancer stem cells. Cancer Letters 2013; 332(2) doi: 10.1016/j.canlet.2011.01.013
|
| 66 |
Nian Ma, Dipayan Bose, Erle S. Robertson. Comprehensive Toxicology. 2026; doi: 10.1016/B978-0-323-95488-4.00114-5
|
| 67 |
Hannah Powell, Cristian Coarfa, Elisa Ruiz-Echartea, Sandra Grimm, Omar Najjar, Bing Yu, Luis Olivares, Michael Scheurer, Christie Ballantyne, Abeer Alsarraj, Emad Salem, Aaron Thrift, Hashem El Serag, Salma Kaochar. Differences in Prediagnostic Serum Metabolomic and Lipidomic Profiles Between Cirrhosis Patients with and without Incident Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma 2024; doi: 10.2147/JHC.S474010
|
| 68 |
Peiying Yang, Yan Jiang, Yong Pan, Xiaoping Ding, Patrea Rhea, Jibin Ding, David H. Hawke, Dean Felsher, Goutham Narla, Zhimin Lu, Richard T. Lee. Mistletoe extract Fraxini inhibits the proliferation of liver cancer by down-regulating c-Myc expression. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-41444-2
|
| 69 |
Alexandra V. Schmidt, Satdarshan P. Monga, Edward V. Prochownik, Eric S. Goetzman. A Novel Transgenic Mouse Model Implicates Sirt2 as a Promoter of Hepatocellular Carcinoma. International Journal of Molecular Sciences 2023; 24(16) doi: 10.3390/ijms241612618
|
| 70 |
Han Han, Dan Sun, Wenjuan Li, Hongxing Shen, Yahui Zhu, Chen Li, Yuxing Chen, Longfeng Lu, Wenhua Li, Jinxiang Zhang, Yuan Tian, Youjun Li. A c-Myc-MicroRNA functional feedback loop affects hepatocarcinogenesis. Hepatology 2013; 57(6) doi: 10.1002/hep.26302
|
| 71 |
Longfeng Lu, Han Han, Yuan Tian, Wenjuan Li, Jinxiang Zhang, Maohui Feng, Youjun Li. Aurora kinase A mediates c‐Myc's oncogenic effects in hepatocellular carcinoma. Molecular Carcinogenesis 2015; 54(11) doi: 10.1002/mc.22223
|
| 72 |
Sonya Parpart, Stephanie Roessler, Fei Dong, Vinay Rao, Atsushi Takai, Junfang Ji, Lun-Xiu Qin, Qing-Hai Ye, Hu-Liang Jia, Zhao-You Tang, Xin Wei Wang. Modulation of miR-29 expression by alpha-fetoprotein is linked to the hepatocellular carcinoma epigenome. Hepatology 2014; 60(3) doi: 10.1002/hep.27200
|
| 73 |
Venkatesh Kancherla, Samir Abdullazade, Matthias S. Matter, Manuela Lanzafame, Luca Quagliata, Guglielmo Roma, Yujin Hoshida, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio. Genomic Analysis Revealed New Oncogenic Signatures in TP53-Mutant Hepatocellular Carcinoma. Frontiers in Genetics 2018; 9 doi: 10.3389/fgene.2018.00002
|
| 74 |
Fei Ji, Zhi-heng Zhang, Yi Zhang, Shun-Li Shen, Qing-Hua Cao, Long-Juan Zhang, Shao-Qiang Li, Bao-Gang Peng, Li-Jian Liang, Yun-Peng Hua. Low expression of c-Myc protein predicts poor outcomes in patients with hepatocellular carcinoma after resection. BMC Cancer 2018; 18(1) doi: 10.1186/s12885-018-4379-5
|
| 75 |
Md. Kamrul H. Chowdhury, Lindsay E. Wu, James L.J. Coleman, Nicola J. Smith, Margaret J. Morris, Peter R. Shepherd, Greg C. Smith. Niclosamide blocks glucagon phosphorylation of Ser552 on β-catenin in primary rat hepatocytes via PKA signalling. Biochemical Journal 2016; 473(9) doi: 10.1042/BCJ20160121
|
| 76 |
Bin Chen, Lana Garmire, Diego F. Calvisi, Mei-Sze Chua, Robin K. Kelley, Xin Chen. Harnessing big ‘omics’ data and AI for drug discovery in hepatocellular carcinoma. Nature Reviews Gastroenterology & Hepatology 2020; 17(4) doi: 10.1038/s41575-019-0240-9
|
| 77 |
Alok R. Singh, Shweta Joshi, Adam M. Burgoyne, Jason K. Sicklick, Sadakatsu Ikeda, Yuko Kono, Joseph R. Garlich, Guillermo A. Morales, Donald L. Durden. Single Agent and Synergistic Activity of the “First-in-Class” Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma. Molecular Cancer Therapeutics 2016; 15(11) doi: 10.1158/1535-7163.MCT-15-0976
|
| 78 |
Li Tang, Shuo Zhang, Jia-Cheng Ji, Peng-Jiao Wang, Min Zhang, Pei-Mei Feng, Xiu-Li Gao. Identifying the Mechanisms of Rosa Roxburghii Tratt on Treating Gastric Cancer: Combining the Targetable Screening From the Cancer Genome Atlas With Network Pharmacology. Natural Product Communications 2021; 16(11) doi: 10.1177/1934578X211059646
|
| 79 |
Shahanshah Khan, Hasan Zaki. Crosstalk between NLRP12 and JNK during Hepatocellular Carcinoma. International Journal of Molecular Sciences 2020; 21(2) doi: 10.3390/ijms21020496
|
| 80 |
Suryaa Manoharan, Shreejit Saha, Krishnasanthiya Murugesan, Aksayakeerthana Santhakumar, Ekambaram Perumal. Natural bioactive compounds and STAT3 against hepatocellular carcinoma: An update. Life Sciences 2024; 337 doi: 10.1016/j.lfs.2023.122351
|
| 81 |
Javid Sadri Nahand, Farah Bokharaei‐Salim, Arash Salmaninejad, Abolfazl Nesaei, Fatemeh Mohajeri, Azadeh Moshtzan, Alireza Tabibzadeh, Mohammad Karimzadeh, Mohsen Moghoofei, Arezo Marjani, Shoeleh Yaghoubi, Hossein Keyvani. microRNAs: Key players in virus‐associated hepatocellular carcinoma. Journal of Cellular Physiology 2019; 234(8) doi: 10.1002/jcp.27956
|
| 82 |
Tingting Zhang, Ningning Li, Chaoyang Sun, Yang Jin, Xia Sheng. MYC and the unfolded protein response in cancer: synthetic lethal partners in crime?. EMBO Molecular Medicine 2020; 12(5) doi: 10.15252/emmm.201911845
|
| 83 |
Xiaomeng Gao, Jieqiong You, Yanling Gong, Meng Yuan, Haiying Zhu, Liang Fang, Hong Zhu, Meidan Ying, Qiaojun He, Bo Yang, Ji Cao. WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit. Acta Pharmaceutica Sinica B 2022; 12(3) doi: 10.1016/j.apsb.2021.10.021
|
| 84 |
Yuan Yuan, Hui Cai, Xiao-Jun Yang, Wei Li, Jin He, Tian-Kang Guo, Yi-Rong Chen. Liposome-mediated Induction of Apoptosis of Human Hepatoma Cells by C-Myc Antisense Phosphorothioate Oligodeoxynucleotide and 5-Fluorouracil. Asian Pacific Journal of Cancer Prevention 2014; 15(14) doi: 10.7314/APJCP.2014.15.14.5529
|
| 85 |
Jiao Feng, Jingjing Li, Liwei Wu, Qiang Yu, Jie Ji, Jianye Wu, Weiqi Dai, Chuanyong Guo. Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research 2020; 39(1) doi: 10.1186/s13046-020-01629-4
|
| 86 |
Lin Wang, Xinyu Liu, Haoze Lv, Han Zhang, Rimei Lin, Shan Xu, Chaojing Zhang, Shilei Lou, Zhidong Qiu, Cong Sun, Ning Cui. Research Progress on Natural Products That Regulate miRNAs in the Treatment of Osteosarcoma. Biology 2025; 14(1) doi: 10.3390/biology14010061
|
| 87 |
Chaitra Rai, Hang Ruan, Xue Li, Wenbo Li, Hyun-Hwan Jeong, Chengchuang Song, Panpan Liu, Yingjie Chang, Hao Fang, Udhaya Kumar. S, Yuxiang Sun, M. James You, Dongyin Guan, Zhandong Liu, Leng Han, Xuben Hou, Zheng Sun. Histone deacetylase enzyme activity is not the universal anticancer target of HDAC inhibitors. Signal Transduction and Targeted Therapy 2026; 11(1) doi: 10.1038/s41392-026-02698-1
|
| 88 |
Innovations in the Management of Hepatocellular Carcinoma. American Journal of Therapeutics 2018; 25(3) doi: 10.1097/MJT.0000000000000713
|
| 89 |
Hongwen Zhu, Hua Yu, Hu Zhou, Wencheng Zhu, Xiongjun Wang. Elevated Nuclear PHGDH Synergistically Functions with cMyc to Reshape the Immune Microenvironment of Liver Cancer. Advanced Science 2023; 10(17) doi: 10.1002/advs.202205818
|
| 90 |
AM Attallah, M El-Far, MA Abdelrazek, MM Omran, AA Attallah, AA Elkhouly, HM Elkenawy, K Farid. Combined use of nuclear phosphoprotein c-Myc and cellular phosphoprotein p53 for hepatocellular carcinoma detection in high-risk chronic hepatitis C patients. British Journal of Biomedical Science 2017; 74(4) doi: 10.1080/09674845.2017.1334739
|
| 91 |
Mohammad Khalid Zakaria, Imran Khan, Prashant Mani, Parthaprasad Chattopadhyay, Debi P Sarkar, Subrata Sinha. Combination of hepatocyte specific delivery and transformation dependent expression of shRNA inducing transcriptional gene silencing of c-Myc promoter in hepatocellular carcinoma cells. BMC Cancer 2014; 14(1) doi: 10.1186/1471-2407-14-582
|
| 92 |
A. Ehlers, D. Lenze, H. Broll, J. Zagon, M. Hummel, A. Lampen. Dose dependent molecular effects of acrylamide and glycidamide in human cancer cell lines and human primary hepatocytes. Toxicology Letters 2013; 217(2) doi: 10.1016/j.toxlet.2012.12.017
|
| 93 |
Ryota Shizu, Kouichi Yoshinari. Nuclear receptor CAR-mediated liver cancer and its species differences. Expert Opinion on Drug Metabolism & Toxicology 2020; 16(4) doi: 10.1080/17425255.2020.1746268
|
| 94 |
Jairo A Garcia, Lewis R Roberts. Targeted Therapies for Hepatocellular Carcinoma. 2011; doi: 10.2217/ebo.11.267
|
| 95 |
Moein Ala. Target c-Myc to treat pancreatic cancer. Cancer Biology & Therapy 2022; 23(1) doi: 10.1080/15384047.2021.2017223
|
| 96 |
YUAN TIAN, CHANGJUN HUANG, HAI ZHANG, QINGFENG NI, SHENG HAN, DONG WANG, ZEGUANG HAN, XIANGCHENG LI. CDCA7L promotes hepatocellular carcinoma progression by regulating the cell cycle. International Journal of Oncology 2013; 43(6) doi: 10.3892/ijo.2013.2142
|
| 97 |
Mohammad Khalid Zakaria, Debi P. Sarkar, Parthaprasad Chattopadhyay. Promoter Associated RNA. Methods in Molecular Biology 2017; 1543 doi: 10.1007/978-1-4939-6716-2_14
|
| 98 |
Gong-Quan Li, Wen-Zhi Guo, Yi Zhang, Jing-Jing Seng, Hua-Peng Zhang, Xiu-Xian Ma, Gong Zhang, Jie Li, Bing Yan, Hong-Wei Tang, Shan-Shan Li, Li-Dong Wang, Shui-Jun Zhang. Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression. Oncotarget 2016; 7(3) doi: 10.18632/oncotarget.6275
|
| 99 |
Manasi Kotulkar, Julia Barbee, Diego Paine-Cabrera, Dakota Robarts, Maura O’Neil, Udayan Apte. Role of HNF4α-cMyc Interaction in CDE Diet–Induced Liver Injury and Regeneration. The American Journal of Pathology 2024; 194(7) doi: 10.1016/j.ajpath.2024.03.008
|
| 100 |
Yao Liu, Shandong Pan, Li Liu, Xiangjun Zhai, Jibin Liu, Juan Wen, Yixin Zhang, Jianguo Chen, Hongbing Shen, Zhibin Hu, Rui Medeiros. A Genetic Variant in Long Non-Coding RNA HULC Contributes to Risk of HBV-Related Hepatocellular Carcinoma in a Chinese Population. PLoS ONE 2012; 7(4) doi: 10.1371/journal.pone.0035145
|
| 101 |
Feng Lin, Ruliang Ding, Shuang Zheng, Dongyi Xing, Weiwen Hong, Zhijun Zhou, Jie Shen. Decrease expression of microRNA-744 promotes cell proliferation by targeting c-Myc in human hepatocellular carcinoma. Cancer Cell International 2014; 14(1) doi: 10.1186/1475-2867-14-58
|
| 102 |
Daniela Santo, Patrícia V. Mendonça, Arménio C. Serra, Jorge F.J. Coelho, Henrique Faneca. Targeted downregulation of MYC mediated by a highly efficient lactobionic acid-based glycoplex to enhance chemosensitivity in human hepatocellular carcinoma cells. International Journal of Pharmaceutics 2023; 637 doi: 10.1016/j.ijpharm.2023.122865
|
| 103 |
Z. Zhao, J. Ma, K. Wu, L. Chen, J. Yu, W. Hu, K. Zhang. SATB1 is a potential therapeutic target in intrahepatic cholangiocarcinoma. Clinical and Translational Oncology 2016; 18(9) doi: 10.1007/s12094-015-1449-x
|
| 104 |
Marc Remke, Vijay Ramaswamy, Michael D. Taylor. Medulloblastoma molecular dissection. Current Opinion in Oncology 2013; 25(6) doi: 10.1097/CCO.0000000000000008
|
| 105 |
Dhania Novitasari, Ikuko Nakamae, Noriko Yoneda-Kato, Jun-ya Kato, Yoshitaka Hippo, Yusuke Suenaga, Dyaningtyas Dewi Pamungkas Putri, Edy Meiyanto, Muthi’ Ikawati, Der Jiun Ooi. The Combination of Sorafenib and PGV‐1 Inhibits the Proliferation of Hepatocellular Carcinoma Through c‐Myc Suppression in an Additive Manner: In Vitro Studies. Advances in Pharmacological and Pharmaceutical Sciences 2024; 2024(1) doi: 10.1155/adpp/4297953
|
| 106 |
Xavier Bisteau, Matias Caldez, Philipp Kaldis. The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations. Cancers 2014; 6(1) doi: 10.3390/cancers6010079
|
| 107 |
Shun-Ting Chou, Chien-Yun Hsiang, Hsin-Yi Lo, Hui-Fen Huang, Ming-Tsung Lai, Ching-Liang Hsieh, Su-Yin Chiang, Tin-Yun Ho. Exploration of anti-cancer effects and mechanisms of Zuo-Jin-Wan and its alkaloid components in vitro and in orthotopic HepG2 xenograft immunocompetent mice. BMC Complementary and Alternative Medicine 2017; 17(1) doi: 10.1186/s12906-017-1586-6
|
| 108 |
FENG LIU, XIAOFENG DONG, HONG LV, PENG XIU, TAO LI, FUHAI WANG, ZONGZHEN XU, JIE LI. Targeting hypoxia-inducible factor-2α enhances sorafenib antitumor activity via β-catenin/C-Myc-dependent pathways in hepatocellular carcinoma. Oncology Letters 2015; 10(2) doi: 10.3892/ol.2015.3315
|
| 109 |
Xiaoyuan Jia, Yongyi Chen, Xin Zhao, Chunwei Lv, Jie Yan. Oncolytic vaccinia virus inhibits human hepatocellular carcinoma MHCC97‐H cell proliferation via endoplasmic reticulum stress, autophagy and Wnt pathways. The Journal of Gene Medicine 2016; 18(9) doi: 10.1002/jgm.2893
|
| 110 |
Renato Heidor, Ernesto Vargas-Mendez, Fernando Salvador Moreno. Epigenetics of Cancer Prevention. 2019; doi: 10.1016/B978-0-12-812494-9.00011-1
|
| 111 |
Young-Hoon Song, Soo-Jin Jeong, Hee-Young Kwon, Bonglee Kim, Sung-Hoon Kim, Dong-Youl Yoo. Ursolic Acid from <i>Oldenlandia diffusa</i> Induces Apoptosis <i>via</i> Activation of Caspases and Phosphorylation of Glycogen Synthase Kinase 3 Beta in SK-OV-3 Ovarian Cancer Cells. Biological and Pharmaceutical Bulletin 2012; 35(7) doi: 10.1248/bpb.b110660
|
| 112 |
Roser Pinyol, Jean Charles Nault, Iris M. Quetglas, Jessica Zucman-Rossi, Josep M. Llovet. Molecular Profiling of Liver Tumors: Classification and Clinical Translation for Decision Making. Seminars in Liver Disease 2014; 34(04) doi: 10.1055/s-0034-1394137
|
| 113 |
Surbhi Chouhan, Snahlata Singh, Dipti Athavale, Pranay Ramteke, Vimal Pandey, Jomon Joseph, Rajashekar Mohan, Praveen Kumar Shetty, Manoj Kumar Bhat. Glucose induced activation of canonical Wnt signaling pathway in hepatocellular carcinoma is regulated by DKK4. Scientific Reports 2016; 6(1) doi: 10.1038/srep27558
|
| 114 |
Leila Shafaghati, Zahra Razaghi-Moghadam, Javad Mohammadnejad. A Systems Biology Approach to Understanding Alcoholic Liver Disease Molecular Mechanism: The Development of Static and Dynamic Models. Bulletin of Mathematical Biology 2017; 79(11) doi: 10.1007/s11538-017-0336-8
|
| 115 |
Rehab M Abdel-Megeed, Hassan Z Ghanem, Mai O Kadry. Alleviation of doxorubicin adverse effects via loading into various drug-delivery systems: a comparative study. Therapeutic Delivery 2024; 15(6) doi: 10.4155/tde-2023-0121
|
| 116 |
A. A. Stepanenko, V. M. Kavsan. Immortalization and malignant transformation of Eukaryotic cells. Cytology and Genetics 2012; 46(2) doi: 10.3103/S0095452712020041
|
| 117 |
Saravana Mani, Ourania Andrisani. Hepatitis B Virus-Associated Hepatocellular Carcinoma and Hepatic Cancer Stem Cells. Genes 2018; 9(3) doi: 10.3390/genes9030137
|
| 118 |
ZealD Rawal, VinalA Upadhyay, DipakD Patel, TruptiI Trivedi. Medulloblastoma under siege: Genetic and molecular dissection concerning recent advances in therapeutic strategies. Journal of Pediatric Neurosciences 2020; 15(3) doi: 10.4103/jpn.JPN_166_18
|
| 119 |
Andrew P Wright, Srinath Adusumalli, Kathleen E Corey. Statin therapy in patients with cirrhosis. Frontline Gastroenterology 2015; 6(4) doi: 10.1136/flgastro-2014-100500
|