Advance in metabolism and target therapy in breast cancer stem cells

Table 1 Breast cancer stem cell markers

Marker	Expression	Function	Ref.
CD44	High	Adhesion, intracellular signaling, cellular proliferation, angiogenesis, differentiation, migration, and invasion	Senbanjo et al[123], 2017
CD24	Low	Cell metastasis and proliferation	Jaggupilli et al[124], 2012
ALDH1	High	Cellular proliferation, differentiation, stemness, and self-protection	Tomita et al[40], 2016
CD133	High	Cellular differentiation	Glumac et al[52], 2018
CD49f	High	Tumor initiation, metastasis, and chemoresistance	Meyer et al[125], 2010
CD61	High	Tumor initiation and metastasis	Zhu et al[126], 2019
CD90	High	Cell metastasis	Sauzay et al[127], 2019
EpCAM	High	Cellular proliferation, migration, and invasion	Sauzay et al[128], 2018

CD44: Cluster of differentiation 44; CD24: Cluster of differentiation 24; ALDH1: Aldehyde dehydrogenase 1; CD133: Cluster of differentiation 133; CD49f: Cluster of differentiation 49f; CD61: Cluster of differentiation 61; CD90: Cluster of differentiation 90; EpCAM: Epithelial cell adhesion molecule.