Copyright ©The Author(s) 2020.
World J Stem Cells. Jan 26, 2020; 12(1): 1-7
Published online Jan 26, 2020. doi: 10.4252/wjsc.v12.i1.1
Table 1 Differences of mesenchymal stromal/stem cell niche, cell subpopulations, mesenchymal stromal/stem cell surface in vitro markers and multipotentiality between bone marrow and adipose tissue
TissueMSC nicheCell subpopulationsMSC in vitro surface markersMultipotentiality
Bone marrowSubendosteal and vascularOsteoblasts, Endothelial progenitor and mature cells, Macrophages, MSCsPositive: CD44, CD71, CD73, CD90, CD105, CD106, CD120a andAdipogenic, Chondrogenic, and Osteogenic. Pre-committed into osteogenic lineage.
Hematopoietic stem and progenitor cells, lymphocytes, megakaryocytes, erythrocytes, monocytes, neutrophils, basophils, eosinophilsCD124
Negative: CD14, CD34 and CD45
Adipose tissueVascularAdipocytesPositive: CD13, CD29,Adipogenic, Chondrogenic, and Osteogenic. Pre-committed into adipogenic lineage.
CD44, CD73, CD34, CD36, CD90 and CD105
SVF: Pre-adipocytes, endothelial progenitor and mature cells, macrophages, fibroblasts, MSCsNegative: CD31, CD45, CD235a and CD106