Patient-specific induced pluripotent stem cells as “disease-in-a-dish” models for inherited cardiomyopathies and channelopathies – 15 years of research

Figure 1 Diagram of the overlap of the main genes associated with inherited cardiac conditions. A: Genes associated with inherited cardiomyopathies. Each cardiomyopathy is indicated by a different color. Orange: hypertrophic cardiomyopathy; Green: dilated cardiomyopathy; Blue: left ventricular noncompaction; Purple: arrhythmogenic cardiomyopathy; Red: restrictive cardiomyopathy; B: Genes associated with inherited channelopathies. Blue: long QT syndrome; Purple: short QT syndrome; Orange: Brugada syndrome; Green: catecholaminergic polymorphic ventricular tachycardia. ACM: Arrhythmogenic cardiomyopathy; BrS: Brugada syndrome; CPVT: Catecholaminergic polymorphic ventricular tachycardia; DCM: Dilated cardiomyopathy; HCM: Hypertrophic cardiomyopathy; LQTS: Long QT syndrome; LVNC: Left ventricular noncompaction; RCM: Restrictive cardiomyopathy; SQTS: Short QT syndrome.