Copyright ©The Author(s) 2019.
World J Stem Cells. Aug 26, 2019; 11(8): 464-475
Published online Aug 26, 2019. doi: 10.4252/wjsc.v11.i8.464
Figure 1
Figure 1 Epigenetic regulation of stem cell fate. Chromatin remodeling affects cell behavior and regulates the balance between pluripotency and differentiation. HDACs: Histone deacetylases; Oct-4: Octamer-binding transcription factor 4; Sox-2: Sex determining region Y-box 2; NANOG: Nanog homeobox.
Figure 2
Figure 2 Natural molecules and stem cell fate. Bioactive molecules induce cell proliferation and differentiation, reducing ROS production and apoptosis, through chromatin remodeling and epigenetic modifications. ROS: Reactive oxygen species; HDACs: Histone deacetylases.