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结果: 与正常相比, IBS患者精神症状明显增多(40.2±4.5, t = 2.63, P = 0.047), 抑郁(0.64±0.24, t = 2.53, P = 0.020)和焦虑(0.67±0.30, t = 2.16, P = 0.016)积分明显增高; 在IBS患者中, 睡眠质量和日间功能显著下降, PSQI和睡眠障碍以及安眠药用量显著增加. IBS患者的强迫症状(t = 2.60, P = 0.037)和精神因素(t = 2.71, P = 0.028)积分也明显高于消化性溃疡病患者. 多元回归分析显示睡眠质量和多种精神症状呈负相关(R>0.195, P<0.05).
Sleep quality in patients with irritable bowel syndrome
Jian-Qin He, Wei-An Wang, Pin-Jin Hu, Wei Chen
Jian-Qin He, Wei-An Wang, Pin-Jin Hu, Wei Chen, Department of Gastroenterology, The First Affilated Hospital, Sun Yat-sen University, Guangzhou 510058, Guangdong Province, China
Correspondence to: Pin-Jin Hu, Department of Gastroenterology, The First Affilated Hospital, Sun Yat-sen University, Guangzhou 510058, Guangdong Province, China. pjhumd@vip.163.com
Received: June 27, 2003 Revised: July 15, 2003 Accepted: August 16, 2003 Published online: March 15, 2004
AIM: To investigate the sleep quality in patients with irritable bowel syndrome(IBS) and its relationship with the patients psychiatric symptoms.
METHODS: The quality of sleep and psychiatric symptoms in consecutive 41 patients with IBS according to Rome II criteria were measured by Pittsburgh sleep quality index(PSQI) and symptom checklist-90(SCL-90), respectively. In the meantime, 37 matched heath controls and 35 patients matched patients with peptic ulcer diseases as controls were also evaluated. The relationship between PSQI and psychiatric symptoms was investigated by regression analysis.
RESULTS: Compared with health controls, IBS patients had more psychiatric symptoms(40.2±4.5, t = 2.63, P = 0.047), and higher scores of depression(0.64±0.24, t = 2.53, P = 0.020) and anxiety(0.67±0.30, t = 2.16, P = 0.016). Among IBS patients, the quality of sleep and daily functions significantly decreased. PSQI and sleep disturbances as well as soporific using was markedly increased. The scores of obsessive-compulsive(t = 2.60, P = 0.037), and mental factor(t = 2.71, P = 0.028) were higher in IBS patients than that in patients with peptic ulcer diseases. Multiple regression analysis showed negative relarionship between the quality of sleep and many psychiatric symptoms(R>0.195, P<0.05, respectively).
CONCLUSION: IBS patients have sleep disturbances associated psychiatric symptoms.
Key Words: N/A
Citation: He JQ, Wang WA, Hu PJ, Chen W. Sleep quality in patients with irritable bowel syndrome. Shijie Huaren Xiaohua Zazhi 2004; 12(3): 744-747
SCL-90症状自评量表测评结果显示, 与正常人相比, IBS患者精神症状总积分(40.2±4.5, t = 2.63, P = 0.047)、阳性项目数(0.65±0.31, t = 1.98, P = 0.001)、痛苦水平(1.44±0.57, t = 1.98, P = 0.001)、抑郁(0.64±0.24, t = 2.53, P = 0.020)和焦虑(0.67±0.30, t = 2.16, P = 0.016)评分明显增高; IBS患者的强迫症状(t = 2.60, P = 0.037)、抑郁(t = 1.92, P = 0.045)和精神病性因素(t = 2.71, P = 0.028)评分明显高于PU患者; 而正常人和PU患者在痛苦水平上有显著差别(t = 1.96, P = 0.006).
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