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Endoscopic diagnosis and treatment of submucosal tumors of gastrointestinal tract
Gui-Yong Peng, Dian-Chun Fang, Xiang-Hong Li
Gui-Yong Peng, Dian-Chun Fang, Xiang-Hong Li, Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
Correspondence to: Dr. Gui-Yong Peng, Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. p_guiyong@yahoo.com.cn
Received: May 10, 2003 Revised: May 25, 2003 Accepted: June 2, 2003 Published online: January 15, 2004
AIM: To improve the diagnoses and treatment for submucosal tumors of gastrointestinal tract.
METHODS: Endoscopic ultrasonograpy (EUS) was conducted in 136 patients with submucosal tumors (SMT) in gastrointestinal tract. Endoscopic therapy or surgical operation was taken according to the different layers of SMT.
RESULTS: A total of 33 cases of stromal tumors derived from mucosa; 2 cysts, 8 lipomas, 12 etopic pancreases in stomach and 5 varics in gastric fundus from submucosa; 60 benign stromal tumors and 16 malignant stromal tumors from muscularis; 24 benign stromal tumors from mucosa, 6 benign stromal tumors from muscularis, 4 gastric lipomas, 2 cysts, 6 etopic pancreas in stomach were resected by endoscopy; 28 cases of benign stromal tumors derived from muscularis, 15 malignant stromal tumors, 2 lipoma and 2 etopic pancreas were removed by surgery. 97.7% of SMTs diagnosed by EUS were confirmed further by pathology.
CONCLUSION: Different layers of gastrointestinal tract with SMTs can be distinguished clearly by EUS, leading to definite diagnosis of SMTs. EUS is important to select treating methods of SMTs in gastrointestinal tract. Endoscopic therapy is an effective method for submucosal tumor of gastrointestinal tract.
Key Words: N/A
Citation: Peng GY, Fang DC, Li XH. Endoscopic diagnosis and treatment of submucosal tumors of gastrointestinal tract. Shijie Huaren Xiaohua Zazhi 2004; 12(1): 133-136
Rosch T, Kapfer B, Will U, Baronius W, Strobel M, Lorenz R, Ulm K. Accuracy of endoscopic ultrasonography in upper gastrointestinal submucosal lesions: a prospective multicenter study.Scand J Gastroenterol. 2002;37:856-862.
[PubMed] [DOI]
Ainsworth AP, Mortensen MB, Durup J, Wamberg PA. Clinical impact of endoscopic ultrasonography at a county hospital.Endoscopy. 2002;34:447-450.
[PubMed] [DOI]
Chen TK, Wu CH, Lee CL, Lai YC, Yang SS, Tu TC. Endoscopic ultrasonography to study the causes of extragastric compression mimicking gastric submucosal tumor.J Formos Med Assoc. 2001;100:758-761.
[PubMed] [DOI]
Gress F, Schmitt C, Savides T, Faigel DO, Catalano M, Wassef W, Roubein L, Nickl N, Ciaccia D, Bhutani M. Interobserver agreement for EUS in the evaluation and diagnosis of submucosal masses.Gastrointest Endosc. 2001;53:71-76.
[PubMed] [DOI]
Chen TK, Wu CH, Lee CL, Lai YC, Yang SS. Endoscopic ultrasonography in the differential diagnosis of giant gastric folds.J Formos Med Assoc. 1999;4:261-264.
[PubMed] [DOI]
Kojima T, Takahashi H, Parra-Blanco A, Kohsen K, Fujita R. Diagnosis of submucosal tumor of the upper GI tract by endoscopic resection.Gastrointest Endosc. 1999;50:516-522.
[PubMed] [DOI]
Kohut M, Nowak A, Nowakowska-Dulawa E, Marek T, Kaczor R. Endosonography with linear array instead of endoscopic retrograde cholangiography as the diagnostic tool in patients with moderate suspicion of common bile duct stones.World J Gastroenterol. 2003;9:612-614.
[PubMed] [DOI]
Xi WD, Zhao C, Ren GS. Endoscopic ultrasonography in preoperative staging of gastric cancer: determination of tumor invasion depth, nodal involvement and surgical resectability.World J Gastroenterol. 2003;9:254-257.
[PubMed] [DOI]
Sun S, Wang M, Sun S. Use of endoscopic ultrasound-guided injection in endoscopic resection of solid submucosal tumors.Endoscopy. 2002;34:82-85.
[PubMed] [DOI]
Waxman I, Saitoh Y, Raju GS, Watari J, Yokota K, Reeves AL, Kohgo Y. Gastrointest Endosc. High-frequency probe EUS-assisted endoscopic mucosal resection: a therapeutic strategy for submucosal tumors of the GI tract.Gastrointest Endosc. 2002;55:44-49.
[PubMed] [DOI]
Otani Y, Furukawa T, Suganuma K, Yoshida M, Saikawa Y, Kubota T, Kumai K, Mukai M, Kameyama K, Takami H. Minimally invasive surgery for gastric carcinoid tumor.Biomed Pharmacother. 2002;56:217s-221s.
[PubMed] [DOI]
Ludwig K, Wilhelm L, Scharlau U, Amtsberg G, Bernhardt J. Laparoscopic-endoscopic rendezvous resection of gastric tumors.Surg Endosc. 2002;16:1561-1565.
[PubMed] [DOI]
Tagaya N, Mikami H, Kogure H, Kubota K, Hosoya Y, Nagai H. Laparoscopic intragastric stapled resection of gastric submucosal tumors located near the esophagogastric junction.Surg Endosc. 2002;16:177-179.
[PubMed] [DOI]
Tagaya N, Kita J, Kogure H, Kubota K. Laparoscopic intragastric resection of gastric leiomyoma using needlescopic instruments.Surg Endosc. 2001;15:414.
[PubMed] [DOI]
