Biological characteristics of HCC by ultrasound-guided aspiration biopsy and its clinical application

Table 1 The ratios of cell proliferation of HCC in different diameter and benign hyperplastic nodules (%, ^-x±s)

Characteristics of foci	Number of cases	DNA analysis of each period
		G1 period	S period	G2/Mperiod
The group with HCC > 3 cm (A)	20	40.3 ± 6.8	43.5 ± 7.4	16.2 ± 1.7
The group with HCC ≤ 3 cm(B)	26	57.7 ± 5.8	30.4 ± 5.2	11.9 ± 1.1
The group with IBHN (C)	12	94.8 ± 0.7	2.6 ± 0.5	2.6 ± 0.4

G₁ period A:B A:C B:C P < 0.01; S period A:B P < 0.05, S period B: C A:C P < 0.01; G₂/M period A:B B:C A:C P < 0.01.

Table 2 Cell proliferative ratios of 22 cases with HCC before and after ultrasound-guided interventional therapy (%, ^-x± s)

Time of detect	Each period of cell proliferation (%)
	G1 period	S period	G2/Mperiod
Before therapy(a)	52.6 ± 7.2	37.5 ± 8.1	9.9 ± 1.9
After therapy(b)	94.7 ± 4.1	3.7 ± 2.5	1.6 ± 0.5

a: b of each period P < 0.01.