Changes of CD8+CD28- T regulatory cells in rat model of colitis induced by 2,4-dinitrofluorobenzene

Table 1 Splenic CD8+ T-cell subsets of experimental animals and controls on day 10 after enema

	Experimental colitis (%, n = 16)	Control (%, n = 8)	P value
CD8+CD28- T	11.3 ± 2.26	5.64 ± 1.01	0.0001
CD8+CD28+ T	23.3 ± 6.14	27.8 ± 9.70	0.41
CD8+ T	34.6 ± 7.24	33.5 ± 9.41	0.83
CD8+CD28- T/CD8+ T	33.3 ± 5.49	18.4 ± 7.26	0.003

Table 2 Intraepithelial CD8+ T-cell subsets of experimental animals and controls on day 10 after enema

	Experimental colitis (%, n = 16)	Control (%, n = 8)	P value
CD8+CD28- T	6.50 ± 5.37	1.07 ± 0.65	0.049
CD8+CD28+ T	7.52 ± 3.16	16.9 ± 4.07	0.004
CD8+T	14.0 ± 6.83	18.0 ± 4.06	0.38
CD8+CD28- T/CD8+ T	46.0 ± 14.3	6.10 ± 3.72	0.0001