Original Articles
Copyright ©The Author(s) 2001.
World J Gastroenterol. Apr 15, 2001; 7(2): 208-215
Published online Apr 15, 2001. doi: 10.3748/wjg.v7.i2.208
Table 1 Patient characteristics: risk factors for HCC
VariableNumber/TotalPercentage
Sex
Male72/9576%
Female23/9524%
Markers of past or present HBV infection
Yes25/8529%
No60/8571%
Markers of HCV infection
Yes21/8525%
No64/8575%
Markers of both HBV and HCV-infection
Yes6/857%
No79/8593%
History of alcoholism
Yes31/9034%
No59/9066%
Cirrhosis
Yes79/9484%
No15/9416%
Child score (only cirrhotics)
A29/7937%
B32/7940%
C18/7923%
AFP elevated
Yes61/9167%
No30/9133%
Table 2 Patient characteristics: age and clinical chemistry results
VariableMedian (Range)
Age64 (31-85) years
GPT32 (10-244) U/L
AP214 (2-1490) U/L
Bilirubin1.5 (0.4-14.4) mg/dL
Prothrombin time acc. to Quick83 (25-122)%
Albumen3.4 (1.9-4.6) g/dL
AFP38 (0.9-831000) μg/L
Table 3 Tumor characteristics during initial presentation
VariableNumber/TotalPercentage
Type of tumor growth
One nodule38/9440%
> 1 Nodule31/9434%
Diffuse25/9426%
Size of largest nodule
< 3 cm20/8922%
3 cm-5 cm31/8935%
> 5 cm38/8943%
Involvement of both liver lobes
Yes49/9353%
No44/9347%
Portal vein thrombosis
Yes19/9420%
No75/9480%
Lymph node metastases
Yes10/9211%
No82/9289%
Distant metastases
Yes8/939%
No85/9391%
Presence of ascites
Yes43/9545%
No52/9555%
Tumor stage according to Okuda
I28/9430%
II53/9456%
III13/9414%
Table 4 Comparison of viral parameters with studies reported in the literature
AuthorNumberCirrhosisHBVHCVHBV + HCV (%)Country
Northern/Central Europe
Van Roey154605255NABelgium
Widell95NA2917NASweden
Kubicka26874.635.126.910Germany
Petry10089.522370Germany
Peters86904937NAGermany
This study958429257Germany
Southern Europe
Kuper333NA58123Greece
Stroffolini1148NA12715Italy
Asia
Kubo330NA172653Japan
Shiratori205NA117113Japan
Zhang113NA6311NAChina
Chuang128NA7720NAChina