Matrix metalloproteinase 3 facilitates colorectal cancer progression by enhancing cell proliferation and invasion

Table 1 The correlation between matrix metalloproteinase 3 expression in patients with colorectal cancer and their clinicopathological characteristics and prognosis

Characteristics	n	MMP3 expression		χ2	P value
		Low	High
Gender
Male	54	12	42	0.788	0.373
Female	36	11	25
Age (years)
≤ 60	33	9	24	0.081	0.776
> 60	57	14	43
Tumor size (cm)
≤ 5	52	18	34	5.314	0.021
> 5	38	5	33
Mucinous cancer
Yes	12	2	10	0.575	0.448
No	78	21	57
Pathological grading
I/II	73	20	53	0.689	0.406
III/IV	17	3	14
Vascular invasion
Yes	33	11	22	1.657	0.198
No	57	12	45
Nerve invasion
Yes	19	12	59	13.240	0.001
No	71	11	8
T staging
T1-T2	55	22	33	15.510	0.001
T3-T4	35	1	34
Lymph node status
N0	23	16	7	28.107	0.001
N1-N2	67	7	60
pTNM staging
I/II	56	22	34	14.689	0.001
III/IV	34	1	33

MMP3: Matrix metalloproteinase 3; pTNM: Pathological tumor-node-metastasis.