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©The Author(s) 2025.
World J Gastroenterol. May 21, 2025; 31(19): 106644
Published online May 21, 2025. doi: 10.3748/wjg.v31.i19.106644
Published online May 21, 2025. doi: 10.3748/wjg.v31.i19.106644
Table 1 Expression of pescadillo ribosomal biogenesis factor 1 and programmed death-ligand 1 in gastric cancer and head and neck squamous cell cancer tissues
Negatives | Positive | |
PES1 | 28 (48.28) | 30 (51.72) |
PD-L1 | 24 (41.38) | 34 (58.62) |
Table 2 Relationship between pescadillo ribosomal biogenesis factor 1 expression and clinical features of gastric cancer and head and neck squamous cell carcinoma
Diagnostic trait | n | PES1 | χ2 | P value | |
Negative (n = 28) | Positive (n = 30) | ||||
Sex | 0.222 | 0.637 | |||
Male | 37 | 17 (45.95) | 20 (54.05) | ||
Women | 21 | 11 (52.38) | 10 (47.62) | ||
Age (years) | 0.210 | 0.647 | |||
< 60 | 41 | 19 (46.34) | 22 (53.66) | ||
≥ 60 | 17 | 9 (52.94) | 8 (47.06) | ||
Degree of differentiation | 0.672 | 0.412 | |||
Poorly differentiated | 32 | 17 (53.13) | 15 (46.88) | ||
Moderately to well differentiated | 26 | 11 (42.31) | 15 (57.69) | ||
TNM staging | 8.312 | 0.004 | |||
I-II | 28 | 19 (67.86) | 9 (32.14) | ||
III | 30 | 9 (30.00) | 21 (70.00) | ||
Lymphatic node transfer | 5.287 | 0.021 | |||
Yes | 39 | 15 (38.46) | 24 (61.54) | ||
No | 19 | 13 (68.42) | 6 (31.58) | ||
Infiltration depth | 6.846 | 0.009 | |||
T1/T2 | 25 | 17 (68.00) | 8 (32.00) | ||
T3/T4 | 33 | 11 (33.33) | 22 (66.67) | ||
Tumor diameter (cm) | 0.485 | 0.486 | |||
< 5 | 41 | 21 (51.22) | 20 (48.78) | ||
≥ 5 | 17 | 7 (41.18) | 10 (58.82) | ||
Diabetes | 0.021 | 0.885 | |||
Yes | 15 | 7 (46.67) | 8 (53.33) | ||
No | 43 | 21 (48.84) | 22 (51.16) |
Table 3 Relationship between programmed death-ligand 1 expression and clinical characteristics of gastric cancer and head and neck squamous cell carcinoma
Diagnostic trait | n | PD-L1 | χ2 | P value | |
Negative (n = 24) | Positive (n = 34) | ||||
Sex | 0.879 | 0.349 | |||
Male | 37 | 17 (45.95) | 20 (54.05) | ||
Women | 21 | 7 (33.33) | 14 (66.67) | ||
Age (years) | 0.367 | 0.545 | |||
< 60 | 41 | 18 (43.90) | 23 (56.10) | ||
≥ 60 | 17 | 6 (35.29) | 11 (64.71) | ||
Degree of differentiation | 6.508 | 0.011 | |||
Poorly differentiated | 32 | 18 (56.25) | 14 (43.75) | ||
Moderately to well differentiated | 26 | 6 (23.08) | 20 (76.92) | ||
TNM staging | 0.049 | 0.825 | |||
I-II | 28 | 12 (42.86) | 16 (57.14) | ||
III | 30 | 12 (40.00) | 18 (60.00) | ||
Lymphatic node transfer | 5.525 | 0.019 | |||
Yes | 39 | 12 (30.77) | 27 (69.23) | ||
No | 19 | 12 (63.16) | 7 (36.84) | ||
Infiltration depth | 9.269 | 0.002 | |||
T1/T2 | 25 | 16 (64.00) | 9 (36.00) | ||
T3/T4 | 33 | 8 (24.24) | 25 (75.76) | ||
Tumor diameter (cm) | 0.000 | 0.984 | |||
< 5 | 41 | 17 (41.46) | 24 (58.54) | ||
≥ 5 | 17 | 7 (41.18) | 10 (58.82) | ||
Diabetes | 1.192 | 0.275 | |||
Yes | 15 | 8 (53.33) | 7 (46.67) | ||
No | 43 | 16 (37.21) | 27 (62.79) |
- Citation: Hu XN, Li CF, Huang SM, Nie CL, Pang R. Pescadillo ribosomal biogenesis factor 1 and programmed death-ligand 1 in gastric and head and neck squamous cell carcinoma. World J Gastroenterol 2025; 31(19): 106644
- URL: https://www.wjgnet.com/1007-9327/full/v31/i19/106644.htm
- DOI: https://dx.doi.org/10.3748/wjg.v31.i19.106644