Altered profiles of fecal bile acids correlate with gut microbiota and inflammatory responses in patients with ulcerative colitis

Table 1 Demographics and clinical characteristics of the study subjects

Feature	UC patients	Controls	P value
n	32	23	NA
Age (yr)	37.0 (32.00, 49.75)	32.0 (27.00, 51.00)	0.570
Gender (male:female)	17:15	13:10	0.803
Body mass index (kg/m2)	21.85 ± 3.64	22.75 ± 2.95	0.337
Duration of disease (yr)	2 (0.5, 8)	NA	NA
Mayo score	7.8 ± 1.9b	NA	< 0.001
BSFS score	6.0 (6.0, 6.0)b	4.0 (4.0, 4.0)	< 0.001
Inflammation location
Rectum	9	NA	NA
Left colon	11	NA	NA
Whole colon	12	NA	NA
Disease activity		NA	NA
Mild activity	5	NA	NA
Moderate activity	25	NA	NA
Severe activity	2	NA	NA

^bP < 0.01 vs controls. The data are presented as the mean ± SD or median (interquartile range). UC: Ulcerative colitis; BSFS: Bristol stool form scale; NA: Not applicable.