Basic Study
Copyright ©The Author(s) 2020.
World J Gastroenterol. Nov 28, 2020; 26(44): 6929-6944
Published online Nov 28, 2020. doi: 10.3748/wjg.v26.i44.6929
Table 1 Patient characteristics and univariate analysis
CharacteristicnDisease-free survival
Overall survival
Time (mo)
P value
F
Time (mo)
P value
F
Age, median, yr0.142.170.201.72
≥ 6010742.4649.39
< 609350.4855.79
Gender0.152.100.122.42
Male14243.8650.23
Female5849.5854.82
Bormann type0.0044.980.0043.62
I1569.9369.93
II8845.5751.73
III9429.3536.99
IV315.3325.00
Tumor size0.0028.460.0027.42
≥ 5 cm8731.5139.48
< 5 cm11357.4662.07
Location0.094.910.134.11
Upper4435.2243.33
Middle5649.3354.92
Low10048.9254.31
Lauren type0.620.960.630.93
Intestinal9545.2251.26
Mixed4541.0847.06
Diffuse6050.2356.12
Tumor differentiation0.162.000.191.71
Moderate and well6650.8056.28
Poor13444.5750.74
Vessel invasion0.0016.300.0014.73
Yes5931.0738.83
No14152.0857.54
Perineural invasion0.0011.240.0011.52
Yes5128.0137.39
No14952.1457.41
TNM stage0.00335.890.00360.28
I4266.4566.50
II4764.3668.85
III10918.7028.50
IV25.008.50
AC007991.40.053.770.053.95
Overexpression6853.0258.07
Weak expression13242.7049.24
AC079385.30.0014.230.0014.71
Overexpression9536.2643.94
Weak expression10555.1259.92
AL109615.20.0010.480.029.87
Overexpression11339.0446.05
Weak expression8756.2760.90
Model0.0021.760.0021.34
High risk9537.6644.46
Low risk10553.9159.27
Table 2 Multivariate analysis of significant prognostic factors for survival in gastric cancer patients
VariableDisease-free survival
Overall survival

P value
HR
95%CI
P value
HR
95%CI
Bormann type0.201.260.90-1.770.131.290.93-1.91
Tumor size0.410.860.59-1.240.400.850.59-1.24
Vessel invasion0.060.700.48-1.010.160.760.53-1.11
Perineural invasion0.240.800.56-1.160.090.730.50-1.05
TNM stage0.00106.5030.76-368.770.0094.0830.14-293.65
Model0.042.271.46-3.990.032.641.74-4.27
Table 3 Three-long noncoding RNA model and clinicopathologic parameters
CharacteristicModel
High risk (%)
Low risk (%)
P value
χ2
Age, median, yr0.110.74
≥ 6052 (48.6)55 (51.4)
< 6043 (46.2)50 (53.8)
Gender0.271.23
Male71 (50.0)71 (50.0)
Female24 (41.4)34 (58.6)
Bormann type0.0014.29
I2 (13.3)13 (86.7)
II36 (40.9)52 (59.1)
III56 (59.6)38 (40.4)
IV1 (33.3)2 (66.7)
Tumor size0.063.64
≥ 5 cm48 (55.2)39 (44.8)
< 5 cm47 (41.6)66 (58.4)
Location0.770.52
Upper23 (52.3)21 (47.7)
Middle26 (46.4)30 (53.6)
Low46 (46.0)54 (54.0)
Lauren type0.820.39
Intestinal45 (47.4)50 (52.6)
Mixed23 (51.1)22 (48.9)
Diffuse27 (45.0)33 (55.0)
Tumor differentiation0.201.72
Moderate and well27 (40.9)39 (59.1)
Poor68 (50.7)66 (49.3)
Vessel invasion0.540.38
Yes30 (50.8)29 (49.2)
No65 (46.1)76 (53.9)
Perineural invasion0.063.52
Yes30 (58.8)21 (41.2)
No65 (43.6)84 (56.4)
TNM stage0.0110.85
I13 (31.0)29 (69.0)
II18 (38.3)29 (61.7)
III63 (57.8)46 (42.2)
IV1 (50.0)1 (50.0)