Value of long non-coding RNA Rpph1 in esophageal cancer and its effect on cancer cell sensitivity to radiotherapy

Table 1 Relationship between long non-coding RNA Rpph1 expression and clinicopathological features of esophageal cancer

	n	lncRNA Rpph11	t	P value
Sex			0.226	0.822
Male	48	2.10 ± 0.43
Female	35	2.08 ± 0.35
Age			0.685	0.460
< 60	36	2.06 ± 0.39
≥ 60	47	2.12 ± 0.40
Smoking			0.396	0.693
Yes	29	2.12 ± 0.48
No	54	2.08 ± 0.35
Short-term response			5.828	< 0.001
CR	31	1.82 ± 0.32
Not CR	52	2.26 ± 0.34
T stage			5.190	< 0.001
T1-T2	51	1.94 ± 0.30
T3-T4	32	2.34 ± 0.40
N stage			6.121	< 0.001
N0-N1	55	1.94 ± 0.29
N2-N3	28	2.41 ± 0.40
Clinical stage			5.749	< 0.001
I-II	56	1.95 ± 0.31
III-IV	27	2.40 ± 0.38

¹Data are presented as mean ± standard deviation. CR: Complete response; lncRNA: Long non-coding RNA.

Table 2 Diagnostic value of long non-coding RNA Rpph1 for different pathological parameters

Pathological parameters	AUC	95%CI	Sensitivity	Specificity	Cut-off
Short-term response	0.826	0.735-0.918	67.31%	83.87%	> 2.093
T stage	0.765	0.651-0.879	71.88%	82.35%	> 2.210
N stage	0.835	0.720-0.950	82.14%	90.91%	> 2.254
Clinical stage	0.823	0.723-0.923	70.37%	85.71%	> 2.255

AUC: Area under the curve; Cut-off: The optimal cutting point.