Meta-Analysis
Copyright ©The Author(s) 2019.
World J Gastroenterol. Sep 21, 2019; 25(35): 5376-5387
Published online Sep 21, 2019. doi: 10.3748/wjg.v25.i35.5376
Table 1 Characteristics of the included studies
Included studiesStudy designNo. of patientsOutcomes
Funding and conflict of interest statement
Primary (positive LN status)Secondary (R, DSS, complications)
Ahlman et al[13], 1994Single-center restrospective cohort study112/11 (data available at the individual level)Median follow-up 5 yr; 100% 5-yr DSSFunding: Swedish Mekong River Commission, Swedish Cancer Society, Jubileumsklinikens Cancer Research Fund, Sahlgrenska Hospital Research Foundation, Göteborg Medical Society, Assar Gabrielsson Research Foundation, Östergötland County Council and AB Hässle.
Borch et al[19], 2005Multi-center prospective cohort study514/51 (data not available at the individual level)5-yr DSS reported for LN status and type of intervention strata. R also reported for different strata.No funding or conflict of interest reported.
Chen et al[18], 2013Single-center retrospective cohort study562/56 (data not available at the individual level)100% 5- and 10 yr DSS reported.Funding: National Center for Advancing Translational Studies. The authors report no conflicts of interest.
Kim et al[25], 2010Single-center retrospective cohort study221/22 (data not available at the individual level)Mean follow-up 68months for GC cohort; 5-yr DSS 100%. R: 15/22No funding or conflict of interest reported
Louthan et al[24], 2014Single-center retrospective cohort study180/18 (data not available at the individual level)Mean follow-up 47 months for GC cohort; 100% 5-yr DSS for type of intervention strata.Funding: RVO VFN64165 and PRVOUK-P25/LF1/2.
Rappel et al[22], 1995Single-center retrospective cohort study880/88 (data not available at the individual level)Median follow-up 72.2 mo; 100% 5-yr DSS; R: 26/54No funding or conflict of interest information mentioned in the article.
Rindi et al[14], 1996Multi-center retrospective cohort study1522/152 (data not available at the individual level)Mean follow up 58months; 5-yr DSS 100%; R: 77/119No funding or conflict of interest information mentioned in the article.
Safatle-Ribeiro et al[15], 2006Single-center restrospective cohort study131/13 (data available at the individual level)Median follow-up 72.2 moNo funding or conflict of interest information mentioned in the article.
Sagatun et al[17], 2016Single-center restrospective cohort study265/26 (data not available at the individual level)Median follow-up not reported; 5-yr DSS not properly reportedNo funding or conflict of interest reported.
Sato et al[20], 2014Multi-center retrospective cohort study820/82 (data not available at the individual level)Median follow-up reported for different strata. 5-yr DSS not reported; R: 2/82.No funding or conflict of interest reported.
Schindl et al[21], 2001Single-center retrospective cohort study160/16 (data not available at the individual level)Median follow-up 70.3 mo; 5-yr DSS 100%.No funding or conflict of interest information mentioned in article.
Thomas et al[23], 2013Multi-center retrospective cohort study1112/111 (data not available at the individual level for all cases).Mean follow up 76 mo; DSS not reported. R:8/111Funding: Selander foundation. No conflict of interest reported.
Vanoli et al[16], 2018Multi-center retrospective cohort study1236/123 (data not available at the individual level)Median follow up 87 mo. 5-yr DSS reported for different strata.Funding: Internal university grants and the Associazione Italiana Ricerca sul Cancro; Fellowship from San Matteo Hospital Foundation. Conflict of interest: Novartis Pharma and Ipsen Pharma.
Table 2 Newcastle-Ottawa scale cohort star template
Included studiesSelectionComparabilityOutcome
Ahlman et al[13], 1994******
Borch et al[19], 2005********
Chen et al[18], 2015******
Kiim et al[25], 2010******
Louthan et al[24], 2014******
Rappel et al[22], 1995******
Rindi et al[14], 1996*******
Safatle-Ribeiro et al[15], 2006*******
Sagatun et al[17], 2016*****
Sato et al[20], 2014*****
Schindl et al[21], 2001******
Thomas et al[23], 2013******
Vanoli et al[16], 2018*******