Assessment of chronic radiation proctopathy and radiofrequency ablation treatment follow-up with optical coherence tomography angiography: A pilot study

Table 1 Patient demographics and baseline clinical status

Patient demographics (n = 10)
Age, mean (range)	73 (67-85)
Sex, male, No. (%)	10 (100)
Race, white, No. (%)	10 (100)
CRP Patients (n = 8)
Prior treatment	RFA-naïve, n = 5	Previously-treated, n = 3
Prior RFA sessions, mean (range)	0 (0)	2 (1-3)	P value
Baseline RTD score, mean ± SD	2 ± 0.7	0.3 ± 0.6	0.007
Baseline Hgb, g/dL, mean ± SD	13.7 ± 1.8	12 ± 0.8	0.23

Hgb: Hemoglobin concentration; SD: Standard deviation; CRP: Chronic radiation proctopathy; RFA: Radiofrequency ablation; RTD: Rectal telangiectasia density.

Table 2 Endoscopic rectal telangiectasia density scores and occurrence of abnormal rectal mucosal and submucosal microvasculature based on en face optical coherence tomography angiography images

Category	Total patients/visits	Endoscopy	En face OCTA
		RTD ± SD	Abnormal mucosal microvasculature, n (%)	Abnormal submucosal microvasculature, n (%)
Normal patients	2	Not assessed	0 (0)	1 (50)
RFA-naïve patients	5	2.0 ± 0.7	3 (60)	5 (100)
RFA-follow-up visit	8	0.5 ± 0.8	0 (0)	2 (13)

SD: Standard deviation; RFA: Radiofrequency ablation; RTD: Rectal telangiectasia density; OCTA: Optical coherence tomography angiography.

Table 3 Occurrence of abnormal rectal mucosal and submucosal microvasculature in chronic radiation proctopathy patients based on en face optical coherence tomography angiography images, stratified by endoscopic rectal telangiectasia density score

RTD	Total visits	En face OCTA
		Abnormal mucosal microvasculature, n (%)	Abnormal submucosal microvasculature, n (%)
0	5	0 (0)	1 (20)
1	3	0 (0)	2 (66)
2	4	2 (50)	3 (75)
3	1	1 (100)	1 (100)

RTD: Rectal telangiectasia density; OCTA: Optical coherence tomography angiography.