Lee SM, Kim HS, Lee S, Lee JW. Emerging role of 18F-fluorodeoxyglucose positron emission tomography for guiding management of hepatocellular carcinoma. World J Gastroenterol 2019; 25(11): 1289-1306 [PMID: 30918424 DOI: 10.3748/wjg.v25.i11.1289]
Corresponding Author of This Article
Jeong Won Lee, MD, PhD, Associate Professor, Department of Nuclear Medicine, Catholic Kwandong University College of Medicine, International St. Mary’s Hospital, 25, Simgok-ro 100 beon-gil, Seo-gu, Incheon 22711, South Korea. firstname.lastname@example.org
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Patients beyond the Milan criteria with a negative PET finding had comparable recurrence-free survival in comparison with those within the Milan criteria
FDG: 18F-fluorodexoyglucose; PET: Positron emission tomography; HCC: Hepatocellular carcinoma; Tmax/Lmax: Maximum FDG uptake of tumor-to-maximum FDG uptake of the normal liver ratio; TLR: Tumor-to-non-tumor liver uptake ratio; SUV: Standardized uptake value; AFP: Alpha-fetoprotein; UCSF: University of California San Francisco; ROC: Receiver operating characteristic.
Table 4 Current literature evaluating the prognostic value of 18F-fluorodexoyglucose positron emission tomography in hepatocellular carcinoma patients with treatments other than surgical resection and liver transplantation
TLR was significant predictor for progression-free survival and overall survival
FDG: 18F-fluorodexoyglucose; PET: Positron emission tomography; HCC: Hepatocellular carcinoma; TLR: Tumor-to-non-tumor liver uptake ratio; ΔTSUVmax%: Relative changes of maximum FDG uptake of tumor between pre-therapeutic and post-therapeutic FDG PET scans; SUV: Standardized uptake value; TACE: Transarterial chemoembolization; CCRT: Concurrent chemoradiotherapy; SABR: Streotactic ablative radiotherapy; AFP: Alpha-fetoprotein.
Citation: Lee SM, Kim HS, Lee S, Lee JW. Emerging role of 18F-fluorodeoxyglucose positron emission tomography for guiding management of hepatocellular carcinoma. World J Gastroenterol 2019; 25(11): 1289-1306