Basic Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Feb 14, 2018; 24(6): 657-670
Published online Feb 14, 2018. doi: 10.3748/wjg.v24.i6.657
Table 1 Demographics and results of mycobacterium avium subspecies paratuberculosis presence and frequency of PTPN2:rs478582/PTPN22:rs2476601 in CD subjects
Sample codeGenderAgeDiagnosisMAP +/-PTPN2:rs478582PTPN22:rs2476601
RCS1M50CD-TCGA
RCS2F25CD-TCGA
RCS3F68CD+TCGG
RCS4M26CD+CCGG
RCS5F56CD+CCGG
RCS6NANACD+TCGG
RCS7M60CD+TCGG
RCS8M43CD+TCGG
RCS9F54CD-CCGG
RCS10F31CDNATCGG
RCS11M21CD+NAGG
RCS12M25CD+CCGG
RCS13F40CD+TCGG
RCS14M36CD+TCGG
RCS15NANACD-CCGA
RCS16F25CD+TCGG
RCS17F27CD+TCGG
RCS18M20CD-TTGG
RCS19M25CD+CCGA
RCS20F41CD-TCGG
RCS21M20CD-TTGG
RCS22M40CD-TCGG
RCS23M30CD-TCGG
RCS24F60CD+TCGG
RCS25F39CD+TTGG
RCS26F30CD+CCGA
RCS27F43CD+CCGG
RCS28M30CD+TCGA
RCS29M28CD+TCGG
RCS30M66CD+TTGG
RCS31M53CD-TTGG
RCS32M28CD-TCGA
RCS33F38CD+CCGG
RCS34M44CD-CCGA
RCS35M53CD-TCGG
RCS36M24CD+TCGG
RCS37F51CD+TCGG
RCS38F46CD+TCGG
RCS39M24CD-CCGG
RCS40F63CD+TCGG
RCS41F25CD-TCGG
RCS42F66CD-TCGG
RCS43F27CD+TCGG
RCS44F25CD+TCGG
RCS45F38CD+TCGG
RCS46F26CD-CCAA
RCS47M54CD+TTGA
RCS48F31CD+TCGG
RCS49M56CD-CCGG
RCS50F53CD-TCGG
RCS51F51CD-TTGA
RCS52F23CD+TCGG
RCS53M26CD+TCGG
RCS54M38CD-TTGG
RCS55F31CD+TCGG
RCS56M61CD+TCGG
RCS57F24CD+TCGG
RCS58M57CD-CCGG
RCS59F30CD+TTGG
RCS60M51CD-CCGG
RCS61F55CD-CCGG
RCS62F61CD-TTGG
RCS63F31CD+TCGG
RCS64F56CDNATCGG
RCS65M25CD+NANA
RCS66F53CD+NANA
RCS67M30CD-TCGG
RCS68F49CD-CCGG
RCS69M28CD+TTGG
RCS70M26CD+TTGG
RCS71M26CD+CCGG
RCS72M58CD+CCGG
Table 2 MAP IS900 nPCR presence and correlation with PTPN2:rs478582/PTPN22:rs2476601 in clinical subjects
MAP presence
HealthyCDOR (95%CI)

Overall4/48 (9.33%)43/70 (61.4%)a17.5 (5.65–54.3)a
rs478582
TT2/17 (11.8%)6/12 (50%)a7.5 (1.17-48.2)a
TC0/22 (0%)25/37 (67.6%)91.8 (5.14-1604.3)a
CC2/8 (25%)9/19 (47.4%)2.7 (0.43-16.9)
TC + CC2/30 (6.67%)34/56 (60.7%)a21.6 (4.68-100.1)a
rs2476601
GG4/59 (6.78%)33/59 (55.9%)a17.6 (5.59-54.4)a
GA0/4 (0%)3/10 (30.0%)4.2 (0.17-101.5)
AA0/1 (0%)0/1 (0%)1.00 (0.02-92.4)
GA + AA0/5 (0%)3/11 (27.3%)4.53 (0.19-105.8)
Haplotypes
T-G2/15 (13.3%)5/10 (50.0%)a6.5 (0.94-45.1)a
C-G2/29 (6.90%)31/46 (67.4%)a30.0 (6.3-142.6)a
T-A0/2 (0%)1/2 (50.0%)5.00 (0.11-220.6)
C-A0/2 (0%)3/9 (33.3%)2.69 (0.1-73.2)