Ubiquitin-like modifier activating enzyme 2 promotes cell migration and invasion through Wnt/β-catenin signaling in gastric cancer

Table 1 Correlations of ubiquitin-like modifier activating enzyme 2 expression and clinicopathological characteristics

Characteristic	Cases	Uba2 expression
		Low, negative and low	High, moderate and strong
Age in yr
< 60	39	8	31
≥ 60	61	16	45
Gender
Male	74	19	55
Female	26	5	21
Tumor size in cm
< 5	59	16	43
≥ 5	41	8	33
Lauren classification
Intestinal	24	11	13b
Diffuse	44	4	40
Mixed	32	9	23
Differentiation
Moderate or well	43	18	25c
Poor	57	6	51
TNM stage
I/II	41	14	27a
III/IV	59	10	49
pT-category
T1,T2	33	12	21a
T3,T4	67	12	55
pN-category
N0	28	11	17a
N1,N2,N3	72	13	59
Vascular invasion
Yes	74	14	60a
No	26	10	16
Perineural invasion
Yes	62	11	51
No	38	13	25

^aP < 0.05,

^bP < 0.01, and

^cP < 0.001 for low Uba2 expression vs high Uba2 expression. Uba2: Ubiquitin-like modifier activating enzyme 2.