Novel serum microRNAs panel on the diagnostic and prognostic implications of hepatocellular carcinoma

Table 1 Demographic and clinical features of the hepatocellular carcinoma patients and normal controls n (%)

Variables	HCC (n = 149)	Normal controls (n = 149)	P value
Average age (yr)	52.7 ± 10.84	51.5 ± 8.26	0.3101
Age (yr)			0.1582
≤ 59	56 (37.6)	68 (45.6)
> 59	93 (62.4)	81 (54.4)
Sex			0.1482
Male	101 (67.8)	89 (59.7)
Female	48 (32.2)	60 (40.3)
Alcohol consumption			0.0692
Ever or Current	104 (69.8)	89 (59.7)
Never	45 (30.2)	60 (40.3)
TNM Stage
I	5 (3.4)
II	12 (8.0)
IIIA	53 (35.6)
IIIB	63 (42.3)
IVA	14 (9.4)
IVB	2 (1.3)
Differentiation grade
High	25 (16.8)
Middle	81 (54.4)
Low	43 (28.9)

¹ Student-t test;

² Two-sided χ² test. HCC: Hepatocellular carcinoma.

Table 2 Risk score analysis of hepatocellular carcinoma patients and normal controls

Score	0-2.258	> 2.258	PPV	NPV
Normal subject (n = 84)	76	8		0.87
HCC (n = 84)	11	73	0.90
Total	87	81

HCC: Hepatocellular carcinoma; PPV: Positive predictive value; NPV: Negative predictive value.