Copyright ©The Author(s) 2018.
World J Gastroenterol. Jun 7, 2018; 24(21): 2311-2319
Published online Jun 7, 2018. doi: 10.3748/wjg.v24.i21.2311
Table 1 Main characteristics of the studies included
StudyStudy designCountryParameterPatients
Etiology of BRESFollow-up (mo)Complication
Kochhar et al[13] 1999CrossoverIndiaPDI1414Mixed2310
Kochhar et al[14] 2002CrossoverIndiaPDI7171Mixed5900
Ahn et al[16] 2015CrossoverNew ZealandPDI2525Mixed9000
Nijhawan et al[16] 2016CrossoverIndiaPDI1111Corrosive1800
Dunne et al[17] 1999RCTUnited StatesTNRD, DS2022Mixed6000
Altintas et al[18] 2004RCTTurkeyTNRD1110Mixed4811
Orive-Calzada et al[20] 2012CohortSpainTNRD149Mixed4501
Hirdes et al[19] 2013RCTNetherlandTNRD, DS3129Anastomotic3351
Pereira-Lima et al[21] 2015RCTBrazilTNRD, DS910Mixed1300
Camargo et al[22] 2003RCTBrazilDS77Mixed1200
Rupp et al[23] 1995RCTUnited StatesDS2221Mixed1100
Table 2 Results of the Newcastle-Ottawa quality assessment scale for cross-over and cohort studies
Item 1Item 2Item 3Item 4Item 5Item 6Item 7Item 8
Ahn et al[21] 2015-N/A++-?+?Modified NOS
Kochhar et al[21] 2015-N/A++-?++Modified NOS
Kochhar et al[21] 2015+N/A++-?++Modified NOS
Nijhawan et al[21] 2015-N/A++--++Modified NOS
Orive-Calza et al[21] 2015--+?+++?NOS
Table 3 Results of the quality assessment of randomized controlled trials by the JADAD scoring system
Item 1Item 2Item 3Item 4Item 5OverallQuality
Dunne et al[17] 19991-10000Low; 0
Altintas et al[18] 20041-10000Low; 0
Hirdes et al[19] 2013111115High; 5
Pereira-Lima et al[21] 2015111115High ,5
Camargo et al[21] 20031-11-111Low; 1
Rupp et al[21] 19951-10000Low; 0
Table 4 Summary of findings
OutcomesIntervention valuesControl valuesNumber of patientsQuality of evidence (GRADE)Comments
PDI0.335/mo1.355/mo121Very lowOnly studies with cross-over design were analyzed
MD: -1.12
95%CI: -1.99 to -0.25
P = 0.012
TNRDn/an/a165Very lowDifferent length of follow up results in high risk of bias
MD: -1.17
95%CI: -0.24 to 0.05
P = 0.057
DSn/an/a178Very lowDifferent scoring scales were used and different lengths of follow up result in high risk of bias
SMD: 0.35
95%CI: -0.38 to 1.08
P = 0.351