Endoscopic submucosal dissection for early esophageal neoplasms using the stag beetle knife

Table 1 Study demographics and clinicopathologic characteristics n (%)

Characteristics	Value
Number of patients	70
Number of lesions	96
Age, mean ± SD (range), yr	67 ± 10 (43-87)
Sex
Male	59 (84)
Female	11 (16)
Location of the tumor in the esophagus
Upper one-third	11 (11)
Middle one-third	53 (55)
Lower one-third	33 (34)
Gross appearance
Depressed	86 (90)
Elevated	7 (7)
Flat	2 (2)
Mixed	1 (1)
Resected specimen size, mean ± SD (range), mm	33 ± 14 (9-75)
Resected tumor size, mean ± SD (range), mm	24 ± 13 (1-64)
Luminal extent
< 1/2	59 (61)
≥ 1/2, < 2/3	20 (21)
≥ 2/3	17 (18)
Histopathologic features
Dysplasia/intraepithelial neoplasia	21 (22)
Squamous cell carcinoma	75 (78)
Epithelial lining	15 (20)
Lamina propria mucosae	31 (41)
Muscularis mucosae	13 (17)
Submucosa (SM1)	2 (3)
Submucosa (SM2 or deeper)	14 (19)

Table 2 Short-term outcomes and adverse events of esophageal endoscopic submucosal dissection, n %

	95%CI
Procedure duration, median (range)	60 (25-305)
En bloc resection	96 (100) [96.2-100]
Complete resection with negative margins	91 (95) [88.4-97.8]
Curative resection	78 (81) [72.3-87.8]
Adverse events
Perforation	0 (0) [0-3.9]
Delayed bleeding	0 (0) [0-3.9]
Pneumonia	3 (3) [1.1-8.8]
Esophageal stricture	7 (7) [3.6-14.3]