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©The Author(s) 2017.
World J Gastroenterol. Dec 28, 2017; 23(48): 8671-8678
Published online Dec 28, 2017. doi: 10.3748/wjg.v23.i48.8671
Published online Dec 28, 2017. doi: 10.3748/wjg.v23.i48.8671
Table 1 Case series and reports on radical resection for xanthogranulomatous cholecystitis
| Ref. | n | Age (yr) | M:F | Perioperative findings | Intervention | Outcome |
| Agarwal et al[12] Gastrointest Surg, 2013 | 31 | 50 ± 13 | 1:3.3 | Cholelithiasis 55% | Radical cholecystectomy | Postoperative mortality 3% |
| Continuous mucosal line enhancement 48% | ||||||
| GB wall thickening 19% | ||||||
| Hepatic invasion 81% | ||||||
| Intramural hypoattenuating nodules 42% | ||||||
| Jaundice 7% | ||||||
| Mass lesion 100% | ||||||
| Rammohan et al[3] Gastroenterol Res, Pract 2014 | 16 | 56 ± 12 | 1:1.5 | Cholelithiasis 69% | Radical cholecystectomy | NR |
| Continuous mucosal line enhancement 50% | ||||||
| GB wall thickening 37% | ||||||
| Intramural hypoattenuating nodules 56% | ||||||
| Jaundice 13% | ||||||
| Suzuki H, World J Gastroenterol 2015 | 6 | 64 ± 10 | 2:1 | Cholelithiasis 83% | Radical cholecystectomy | NR |
| Continuous mucosal line enhancement 50% | ||||||
| GB wall thickening 50% | ||||||
| Intramural hypoattenuating nodules 50% | ||||||
| Jaundice 17% | ||||||
| Retrograde biliary dilatation 17% | ||||||
| Nacif Souto L, 2017 | 3 | 65 (42-66) | 2:1 | Cholelithiasis 100% | Cholecystectomy + right trisectionectomy + CBD excision + hilar lymphadenectomy + double hepaticojejunostomy (n = 2), radical cholecystectomy + CBD excision + hilar lymphadenectomy + hepaticojejunostomy (n = 1) | Asymptomatic after ≥ 6 yr f/u |
| Continuous mucosal line enhancement 100% | ||||||
| GB wall thickening 100% | ||||||
| Hepatic invasion 67% | ||||||
| Intramural hypoattenuating nodules 33% | ||||||
| Jaundice 100% | ||||||
| Mass lesion 67% | ||||||
| Retrograde biliary dilatation 100% | ||||||
| Krishna R, J Gastrointest Surg 2008[7] | 3 | 55 (48-56) | 2:1 | Cholelithiasis 100% | Cholecystectomy + CBD excision + hepaticojejunostomy (n = 1), right hepatectomy + CBD excision + hepaticojejunostomy (n = 1), Whipple’s procedure (n = 1) | Asymptomatic after ≥ 1 yr f/u |
| GB wall thickening 100% | ||||||
| Jaundice 100% | ||||||
| Mass lesion 33% | ||||||
| Enomoto T, Hepato-gastroenterology 2003 | 1 | 64 | M | Hepatic invasion, jaundice, mass lesion, retrograde biliary dilatation | Cholecystectomy + right hepatectomy + Whipple’s procedure | NR |
| Garg P, J Gastrointest Canc 2014 | 1 | 32 | F | Hepatic invasion, jaundice, mass lesion, retrograde biliary dilatation | Radical cholecystectomy + CBD excision + hepaticojejunostomy | Asymptomatic |
| Goldar-Najafi A, Semin Liver Dis 2003 | 1 | 45 | M | Cholelithiasis, GB wall thickening, jaundice, retrograde biliary dilatation | Whipple’s procedure | NR |
| Kawate S, World J Gastroenterol 2006 | 1 | 34 | F | Jaundice, mass lesion, retrograde biliary dilatation | Cholecystectomy + extended right hepatectomy + CBD excision + hepaticojejunostomy | NR |
| Makino I, World J Gastroenterol 2009 | 1 | 76 | M | GB wall thickening, hepatic invasion | Radical cholecystectomy | Asymptomatic after 8 mo f/u |
| Martins P, Hepatobiliary Pancreat Dis Int 2012 | 1 | 35 | M | GB wall thickening, hepatic invasion, jaundice | Cholecystectomy + left trisectionectomy + CBD excision + hilar lymphadenectomy + hepaticojejunostomy | Asymptomatic after 6 mo f/u |
| Pantanowitz L, Pathol Int 2004 | 1 | 75 | F | Mass lesion, retrograde biliary dilatation | Cholecystectomy + extended left hepatectomy | NR |
| Sharma D, ANZ J Surg 2009 | 1 | 52 | F | Cholelithiasis, hepatic invasion, mass lesion | Radical cholecystectomy | Uneventful postoperative course |
| Spinelli A, World J Gastroenterol 2006 | 1 | 46 | F | Cholelithiasis, jaundice, mass lesion, retrograde biliary dilatation | Cholecystectomy + right hepatectomy + CBD excision + segmental duodenal resection + right hemicolectomy + partial omentectomy + hepaticojejunostomy + ileotransversostomy | Asymptomatic after 1 yr f/u |
| Total | 68 | 53 ± 7 | 1:1.7 | Cholelithiasis 62% | Postoperative mortality 1% | |
| Continuous mucosal line enhancement 43% | ||||||
| GB wall thickening 35% hepatic invasion 47% | ||||||
| Intramural hypoattenuating nodules 38% | ||||||
| Jaundice 25% | ||||||
| Mass lesion 72% | ||||||
| Retrograde biliary dilatation 15% |
- Citation: Nacif LS, Hessheimer AJ, Rodríguez Gómez S, Montironi C, Fondevila C. Infiltrative xanthogranulomatous cholecystitis mimicking aggressive gallbladder carcinoma: A diagnostic and therapeutic dilemma. World J Gastroenterol 2017; 23(48): 8671-8678
- URL: https://www.wjgnet.com/1007-9327/full/v23/i48/8671.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i48.8671