Copyright ©The Author(s) 2017.
World J Gastroenterol. Oct 14, 2017; 23(38): 6927-6930
Published online Oct 14, 2017. doi: 10.3748/wjg.v23.i38.6927
Table 1 Advantages and pitfalls of function tests for pancreatic exocrine insufficiency
Aspiration of pancreatic contents (during secretin-cholecystokinin/cerulein administration)High sensitivityInvasive; only available in specialized centers
CFAGold standard; useful in monitoring PERTNeed of a strict diet; unpleasant and long stool collection; no simultaneous PERT
FE-1Easy test; widely available; no need to stop PERTLow sensitivity in mild PEI; not clear cut-off
Acid steatocritGood correlation with CFALack of standardization; Influenced by dietary fat intake
13C-mixed Triglyceride Breath TestGood sensitivity in detecting mild to moderate PEI; useful in monitoring PERTOnly available in specialized center; false positive results in non pancreatic fat malabsorpion