Efficacy and safety of stellate ganglion block in chronic ulcerative colitis

Table 1 Clinical symptoms in the control and experimental groups before treatment n (%)

Indices (clinical symptoms)	Control group (n = 30)	Experimental group (n = 90)	t/χ2	P value
Stomach ache	17 (56.67)	50 (55.56)	0.025	0.874
Time to defecation (-x ± s)	8.50 ± 1.31	8.71 ± 1.40	-0.723	0.471
Blood and pus	10 (33.33)	29 (32.22)	0.028	0.867
Tenesmus	13 (43.33)	38 (42.22)	0.025	0.874
Interleukin-8 (ng/L)	25.83 ± 3.01	24.97 ± 2.98	1.366	0.175

Table 2 Clinical symptoms of patients in the two groups after treatment n (%)

Group	Stomach ache	Time to defecation (-x ± s )	Blood and pus	Tenesmus
Control group
Before treatment	17 (56.67)	8.50 ± 1.31	10 (33.33)	13 (43.33)
After treatment	13 (43.33)	2.91 ± 0.97	5 (16.67)	7 (23.33)
t/χ2	3.548	18.784	7.401	9.000
P value	0.060	0.000	0.007	0.003
Experimental group
Before treatment	50 (55.56)	8.71 ± 1.40	29 (32.22)	38 (42.22)
After treatment	8 (8.89)a	1.12 ± 0.87a	4 (4.44)a	6 (6.67)a
t/χ2	49.864	43.684	25.776	34.213
P value	0.000	0.000	0.000	0.000

^aP < 0.05 vs the control group.

Table 3 Comparison of interleukin-8 expression levels between the control and experimental groups

Group	Different time points				Mean	F	P value
	Day 0	Day 10	Day 20	Day 30
Control group	25.83 ± 3.01	25.23 ± 2.87	24.68 ± 2.99	24.34 ± 2.98	25.02 ± 2.95	2.191	0.060
Experimental group	24.97 ± 2.98	22.20 ± 2.90	15.95 ± 2.62	8.81 ± 2.13	17.98 ± 2.54	9.715	0.000
Mean	25.40 ± 2.95	23.72 ± 2.88	20.32 ± 2.71	16.58 ± 2.35	19.26 ± 2.52	6.114	0.008
t	1.366	4.969	15.249	31.117	12.617	(F = 5.491, P = 0.032)1	(F = 2.981, P = 0.139)2
P value	0.175	0.000	0.000	0.000	0.000

¹Overall comparison of F statistics and P values between the control and experimental groups;

²Interactions between F statistics and P values.

Table 4 Adverse reactions in the control and experimental groups after treatment

Group	Stomach discomfort	Liver and kidney dysfunction	Headache	Rashes	Vomiting	Neck pain	Incidence
Control group	5	1	3	2	2	0	43.33%
Experimental group	0	0	0	0	0	7	7.78%