Case Control Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Dec 7, 2016; 22(45): 9966-9973
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.9966
Table 1 Comparison of features of portal hypertension between the groups requiring single liver transplant and those requiring combined liver/kidney transplant (note some patients had > 1 manifestation)
Single organ liver (n = 15 with portal HBP)Combined liver/kidney (n = 4 with portal HBP)P value
Ascites830.582
Varices1100.745
Splenomegaly2720.585
Thrombocytopenia3320.379
Table 2 Comparison of patient demographics between patients with and without portal hypertension
Listing parameterPortal hypertension (n = 19)Non-portal hypertension (n = 28)P value
Age (yr)50.6 (6.4)47.1 (7.4)0.101
Female gender17 (89.5)25 (89.3)0.683
Bilirubin (μmol/L)8 (6-11)8 (6-12)0.965
INR1.1 (1.0-1.2)1.1 (1.0-1.1)0.173
Creatinine (mmol/L)106 (104-436)119 (92-201)0.508
Platelet count (× 109)177 (147-242)234 (198-242)0.012
Sodium (mmol/l)139 (137-143)140 (138-142)0.483
MELD score12 (9-21)11 (8-16)0.422
UKELD score48 (44-50)46 (45-48)0.344
Chronic kidney disease116 (84.2)19 (67.9)0.179
Dialysis dependant3 (15.8)2 (7.1)0.317
Table 3 Intensive care unit requirements and hospital stay between the portal hypertensive and non-portal hypertensive groups in patients receiving a single organ liver transplant
Portal hypertensive group (n = 8)Non-portal hypertensive group (n = 14)P value
Intra-operative
RCC(units)3 (1-4)4 (2-7)0.238
FFP(units)10 (1-18)8 (7-14)0.973
Plts (units)03 (0-10)0.145
ICU stay (d)3 (3-4)2 (2-4)0.188
Hospital stay (d)9 (7-13)10 (7-12)0.973
RRT in ICU immediately post-op2/8 (25%)0/14 (0)0.121
Table 4 Intensive care unit requirements and hospital stay between the portal hypertensive and non-portal hypertensive groups in patients receiving a combined liver/kidney transplant
Portal hypertensive group (n = 4)Non-portal hypertensive group (n = 8)P value
Intra-operative
RCC (units)13 (4-19)9 (3-19)0.933
FFP (units)15 (7-23)14 (5-18)0.683
Plts (units)10 (3-10)10 (0-20)0.683
ICU stay (d)5 (3-7)7 (3-41)0.368
Hospital stay (d)16 (12-18)15 (12-49)0.808
RRT in ICU immediately post-op3/4 (75%)3/8 (37.5%)0.273