Retrospective Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Dec 7, 2016; 22(45): 10038-10044
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.10038
Table 1 General information on patients with serrated lesions in upper gastrointestinal tract
n (%)
Total21
Mean age (yr), mean ± SD55.3 ± 17.2
Gender, male11 (52.4)
Body mass index (kg/m2), mean ± SD24.9 ± 5.8
18.5-23.913 (61.9)
≥ 24.08 (38.1)
History of smoking7 (33.3)
Alcohol consumption10 (47.6)
Family history of gastric cancer1 (4.8)
Indications for endoscopy
Upper abdominal pain5 (23.8)
Nausea, vomit and reflux4 (19.0)
Anemia and edema4 (19.0)
Positive fecal occult blood test3 (14.3)
A history of gastric polyps3 (14.3)
Dyspepsia2 (9.5)
Table 2 Clinical features of serrated lesions in upper gastrointestinal tract
n (%)
Size (mm), mean ± SD11.7 ± 10.3
≤ 58 (38.1)
5-104 (19.0)
10-206 (28.6)
20-301 (4.8)
≥ 302 (9.5)
Distribution
Esophagus1 (4.8)
Cardia3 (14.3)
Corpus9 (42.9)
Antrum5 (23.8)
Duodenum3 (14.3)
Morphology
Serrated hyperplasia6 (28.6)
Hyperplastic polyps8 (38.1)
Adenoma6 (28.6)
Adenocarcinoma1 (4.8)
Situation of serrated lesions in mucosal lesions
Inflammation or ulcer3 (14.3)
Serrated polyps14 (66.7)
Ménétrier gastropathy3 (14.3)
Duodenal cancer1 (4.8)
Colonoscopy findings18
No-polyp4 (22.2)
Hyperplastic polyps7 (38.9)
Non-advanced adenomas3 (16.7)
Advanced adenomas4 (22.2)
Tubular adenoma with high grade dysplasia1 (5.6)
Tubulovillous adenoma2 (11.1)
Adenoma > 10 mm1 (5.6)
Table 3 Colonoscopy findings in the patients with serrated lesions in upper gastrointestinal tract
Serrated lesions in upper gastrointestinal tract mucosal lesions (n)Colonoscopy findings (n)
Inflammation or ulcer (3)HPs (1)
HPs (8)AA (2), NAA (1), HPs (2)
Serrated adenoma (6)AA (2), NAA (2), HPs (2)
Ménétrier gastropathy (3)HPs (2)
Duodenal cancer (1)Absent
Table 4 Prevalence of colorectal adenoma in patients with serrated lesions in upper gastrointestinal tract and the control group n (%)
Patients with serrated lesions in UPGI(n = 18)Average group(n = 72)OR (95%CI)P value
Colorectal adenoma7 (38.9)8 (11.1)5.091 (1.534-16.890)0.010
Non-advanced adenoma3 (16.7)5 (6.9)2.680 (0.576-12.463)0.195
Advanced adenoma4 (22.2)3 (4.2)6.571 (1.322-32.660)0.028