Clinical Trials Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Nov 21, 2016; 22(43): 9595-9603
Published online Nov 21, 2016. doi: 10.3748/wjg.v22.i43.9595
Table 1 Comparison of pH monitoring and gastroesophageal reflux scintigraphy
Gastroesophageal scintigraphy positiveGastroesophageal scintigraphy negativeTotal
pH monitoring positive25934
pH monitoring negative22426
Total471360
Table 2 Comparison of multichannel intraluminal impedance monitoring and gastroesophageal reflux scintigraphy
Gastroesophageal scintigraphy positiveGastroesophageal scintigraphy negativeTotal
MII monitoring positive341044
MII monitoring negative13316
Total471360
Table 3 Comparison of multichannel intraluminal impedance/pH monitoring and gastroesophageal reflux scintigraphy
Gastroesophageal scintigraphy positiveGastroesophageal scintigraphy negativeTotal
MII-pHM positive411051
MII-pHM negative639
Total471360
Table 4 Comparison of multichannel intraluminal impedance and pH monitoring
pH monitoring positivepH monitoring negativeTotal
MII monitoring positive271744
MII monitoring negative7916
Total342660
Table 5 Sensitivity, specificity, positive and negative predictive values of diagnostic tests according to assumed gold standard test
TestGold standard
MII-pH monitoring
GES
Sensitivity, %Specificity, %PPV, %NPV, %Sensitivity, %Specificity, %PPV, %NPV, %
(95%CI)(95%CI)(95%CI)(95%CI)(95%CI)(95%CI)(95%CI)(95%CI)
MII-pHM----87.223.180.433.3
(73.6-94.7)(6.2-54.0)(66.5-89.7)(9.0-69.1)
pHM alone66.710010034.653.230.873.515.4
(52.0-78.9)(62.9-100.0)(87.4-100.0)(17.9-55.6)(38.2-67.6)(10.4-61.1)(55.3-86.5)(5.0-35.7)
MII alone73.310010056.372.323.177.318.6
(73.1-93.8)(62.9-100.0)(90.0-100.0)(30.6-79.2)(57.1-83.9)(6.0-54.0)(61.8-88.0)(5.0-46.3)
GES80.433.387.223.1----
(66.5-89.7)(9.0-69.1)(73.6-94.7)(6.1-54.0)