Iron and non-alcoholic fatty liver disease

Table 1 Proposed mechanisms for the involvement of iron in non-alcoholic fatty liver disease pathogenesis

Site	Mechanism
Hepatic iron	Oxidative Stress[31,53-57]
	Reduced VLDL export[51]
	Macrophage activation[57-59]
	Stellate cell activation[60]
	Endoplasmic reticulum stress[61]
	Increased cholesterol synthesis[62]
Adipose tissue iron	Reduced adiponectin[19,73,74]
	Reduced leptin[76]
	Increased resistin[75]
	Increased lipolysis[77,78]