Endoscopic stenting for inoperable malignant biliary obstruction: A systematic review and meta-analysis

Table 1 Neoplasms distribution in individual studies

Ref.	No. of patients	Bile duct cancer (%)	Pancreatic tumor (%)	Papilae tumor (%)	Gallbladder cancer (%)	Metastatic tumor (%)	Other (%)
Walter et al 2014	2401	0	83	0	0	0	17
Moses et al 2013	85	0	69	3	3	10	15
Mukai et al 2013	60	50	0	0	22	28	0
Sangchan et al 2012	108	100	0	0	0	0	0
Bernon et al 2011	22	NA	NA	NA	NA	NA	NA
Isayama et al 2011	120	0	100	0	0	0	0
Soderlund et al 2006	100	9	78	2	0	7	4
Katsinelos et al 2006	47	17	53	11	0	19	0
Kaassis et al 2003	118	15	75	0	0	0	10
Prat et al 1998	1051	21	64	3	0	12	0
Wagner et al 1993	20	100	0	0	0	0	0
Knyrim et al 1993	62	3	69	5	0	0	23
Davids et al 1992	105	0	100	0	0	0	0

¹Not all patients were included in the meta-analysis.

Table 2 Costs evaluation - per patient in Euros

	Costs (€)
	PS			SEMS
Ref.	No pts	PS cost (mean)	Total	No pts	SEMS cost (mean)	Total
Walter et al, 2014	73	6906	504138	146	6437	939802
Mukai et al, 2013	30	17170.19	515105.7	30	8935.68	268070.4
Soderlund et al, 2006	51	953.1372549	48610	49	940	46060
Katsinelos et al, 2006	24	737.5	17700	23	1308.695652	30100
Kaassis et al, 2003	59	1216.805085	71791.5	59	1208.116949	71278.9
Prat et al, 1998	33	5547	183051	34	4643	157862
Wagner et al, 1993	10	3511.31	35113.1	10	2552.57	25525.7
Knyrim et al, 1993	31	3067.75	95100.25	31	2045.17	63400.27
MEAN (per patient)	4728.648071			4193.977147
SD	5434.740692			2905.677081
	P = 0.0985

SEMS: Self-expanding metal stents; PS: Plastic stents.

Table 3 Time for stent dysfunction - mean time per author in days

Time for dysfunction in days
Ref.	PS	SEMS
Walter et al, 2014	172	293.3
Moses et al, 2013	153.3	385.3
Mukai et al, 2013	112	359
Sangchan et al, 2012	35	103
Isayama et al, 2011	202	285
Soderlund et al, 2006	54	108
Katsinelos et al, 2006	123.5	255
Prat et al, 1998	96	144
Davids et al, 1992	126	273
MEAN	123.7261792	250.2537988
SD	53.38757918	104.0647031
	P < 0.0001

SEMS: Self-expanding metal stents; PS: Plastic stents.