Mast cell tryptase and carboxypeptidase A expression in body fluid and gastrointestinal tract associated with drug-related fatal anaphylaxis

Table 1 Number of tryptase-positive particles in the anaphylaxis and control groups

	Control (× 100)	Anaphylaxis (× 100)
Stomach	4.88 ± 1.56	46.67 ± 11.111
Jejunum	5.21 ± 1.34	48.89 ± 11.021
Lung	1.30 ± 1.02	33.72 ± 5.761
Larynx	1.67 ± 1.03	40.08 ± 7.561
Heart	1.10 ± 0.77	7.11 ± 5.671

¹Denotes significant difference vs control, P < 0.05, n = 10.

Table 2 Expression of tryptase in serum and pericardial fluid

	n	Serum (μg/L)	Pericardial fluid (μg/L)
Control	20	5.40 ± 0.36	4.60 ± 0.48
Anaphylaxis	15	43.50 ± 0.481	28.64 ± 0.321

¹Denotes significant difference vs control, P < 0.05.

Table 3 Expression of carboxypeptidase A in serum and pericardial fluid

	n	Serum (ng/mL)	Pericardial fluid (ng/mL)
Control	20	3.25 ± 2.30	1.43 ± 0.58
Anaphylaxis	15	8.99 ± 3.911	4.34 ± 2.411

¹Denotes significant difference vs control, P < 0.05.