This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
1Hazard ratio for progression to cirrhosis in HBsAb/HBcAb+ patients;
2Advanced fibrosis (Scheuer score > 2);
3Advanced fibrosis (Metavir score F2-F4). NS: Not significant.
Table 2 The studies evaluating the role of hepatitis B virus DNA in serum and/or liver tissue in the development of cirrhosis in surface antigen of hepatitis B virus-negative patients with chronic hepatitis C
1Incidence Rate Ratio for HCC in patients with chronic hepatitis;
2Incidence Rate Ratio for HCC in patients with cirrhosis. CH: Chronic hepatitis; CLD: Chronic liver disease; NS: Not significant; HCC: Hepatocellular carcinoma; HBc: Hepatitis B core.
Table 4 The studies evaluating the role of hepatitis B virus DNA in serum and/or liver tissue in the development of hepatocellular carcinoma in surface antigen of hepatitis B virus-negative patients with chronic hepatitis C
1OBI assessed with immunochemistry for HBsAg and/or HBcAg. OBI: Occult HBV infection; CH: Chronic hepatitis; CLD: Chronic liver disease; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma.
Citation: Coppola N, Onorato L, Pisaturo M, Macera M, Sagnelli C, Martini S, Sagnelli E. Role of occult hepatitis B virus infection in chronic hepatitis C. World J Gastroenterol 2015; 21(42): 11931-11940