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Copyright ©The Author(s) 2015.
World J Gastroenterol. Nov 14, 2015; 21(42): 11893-11903
Published online Nov 14, 2015. doi: 10.3748/wjg.v21.i42.11893
Table 1 Scoring systems for evaluating severity of alcoholic hepatitis
Scoring system
Maddrey DFThe DF, based on the prothrombin time and total bilirubin, is most commonly used in the decision to treat AH. The DF is a prognostic model at baseline, or static model, similar to MELD and GAHS
MELDThe MELD score, calculated from creatinine, total bilirubin, and international normalized ratio, is classically used for liver transplantation waitlist prioritization but can also be applied as a prognostic indicator in AH
GAHSThe GAHS is calculated based on age, white blood cell count, blood urea nitrogen, total bilirubin, and prothrombin time. The GAHS is another static model that can identify patients at high risk for short-term mortality
Lille scoreThe Lille model is a dynamic model, which includes the baseline total bilirubin level and the total bilirubin seven days into treatment. Other variables included in the model are age, albumin, creatinine, and prothrombin time. The Lille model is most accurate among these scoring systems in identifying the degree of response to therapy in AH[97]