Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis

Table 1 Comparison of liver index, blood lipid and liver functions among the experimental groups (mean ± SD)

Group	n	Liver index (%)	TG (mmol/L)	TC (mmol/L)	ALT (U/L)	AST (U/L)
Normal group	18	2.35 ± 0.18	0.35 ± 0.12	0.91 ± 0.05	45.23 ± 2.23	83.52 ± 6.67
Model group	18	3.80 ± 0.30	0.73 ± 0.15	1.50 ± 0.07	85.12 ± 3.38	130.23 ± 3.23
Treatment group	18	3.20 ± 0.18	0.40 ± 0.07	1.10 ± 0.03	50.10 ± 1.67	85.30 ± 6.63
F		37.97	8.77	87.18	92.16	72.98
P value		0.000	0.017	0.000	0.000	0.000

TG: Triglycerides; TC: Total cholesterol; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.

Table 2 Evaluation of fatty degeneration of hepatocytes, liver lobular inflammatory reactions, balloon-like changes and nonalcoholic fatty liver diseases activity score among the experimental groups

Group	n	Fatty degeneration of hepatocytes (0-3)		Liver lobular inflammatory reactions (0-3)		Balloon-like changes (0-2)		NAS (0-8)
		0-1	2-3	0-1	2-3	0	1-2	0-2	3-4	5-8
Normal group	18	18	0	18	0	18	0	18	0	0
Model group	18	0	18	8	10	2	16	0	1	17
Treatment group	18	2	16	12	6	3	15	3	5	10

NAS: NAFLD activity score.