Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphomas: A review

Table 1 Comparison of Helicobacter pylori-positive and Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphomas

	H. pylori-positive	H. pylori-negative
Pathogenesis	H. pylori infection	Genetic alterations
		Other bacterial infection
		Autoimmune diseases
First-line therapy	Antibiotic therapy	Antibiotic therapy
Response rate for antibiotic therapy	75%	28%

H. pylori: Helicobacter pylori.

Table 2 Previous reports on Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphomas n (%)

Responding patients/treated patients (responding rate)
Steinbach et al[45] (1999)	0/6 (0)
Ruskoné-Fourmestraux et al[30] (2001)	0/10 (0)
Ye et al[14] (2003)	0/5 (0)
Nakamura et al[3] (2006)	2/7 (29)
Raderer et al[4] (2006)	5/6 (83)
Akamatsu et al[46] (2006)	1/9 (11)
Terai et al[47] (2008)	1/4 (25)
Park et al[48] (2010)	3/4 (75)
Asano et al[49] (2012)	5/17 (29)
Choi et al[50] (2013)	2/5 (40)
Raderer et al[52] (2015)	5/13 (46)