Retrospective Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jun 21, 2015; 21(23): 7233-7241
Published online Jun 21, 2015. doi: 10.3748/wjg.v21.i23.7233
Table 1 Inclusion and exclusion criteria
Inclusion and exclusion criteria
Inclusion criteria (all of the following)
Small bowel plus colonic Crohn's disease
Non-stricturing, non-penetrating phenotype
Corticosteroid-free remission (Harvey-Bradshaw Index < 5)
Follow-up ≥ 1 yr
Age ≥ 18 yr
Exclusion criteria (any of the following)
Pregnancy
Intestinal obstruction/obstructive symptoms
Intestinal surgery
Non-steroidal anti-inflammatory drug use within 4 wk of enrolment
Table 2 Hematological results at diagnosis and follow-up (mean ± SD)
ResultDiagnosisFollow-upReference
Hemoglobin (g/dL)13.2 ± 2.814.2 ± 1.412.0-18.0
Leucocytes (103/μL)10.100 ± 3.2007.800 ± 2.8004.8-10.8
Platelets (103/μL)363 ± 194265 ± 124150-350
Erythrocyte sedimentation rate (mm/h)28.6 ± 23.812.3 ± 8.30-14
C-reactive protein (mg/L)42.6 ± 36.417.2 ± 17.0< 2.9
Ferritin (ng/mL)120 ± 11274 ± 4926-388
Albumin (ng/mL)4.1 ± 0.63.9 ± 0.33.1-17.5
Table 3 Patient characteristics, Crohn's disease therapy and endoscopic findings
PatientAge (yr)SexFollow-up (mo)TherapySBCE LSIndex colonoscopy colon findingsPCC2 LSPCC2 colon findings
121Male48Azathioprine 2.5 mg/kg per day2980Extensive ulcers and erythema in entire colon1068Extensive ulcers in entire colon
221Female63Azathioprine 2.5 mg/kg per day Adalimumab 40 mg eow1440Extensive ulcers and erythema in entire colon2336No lesions
326Male57Azathioprine 2.5 mg/kg per day Adalimumab 40 mg eow1350Aphtoid ulcers and erythema in the sigmoid562No lesions
448Male33Azathioprine 2.5 mg/kg per day1240Aphtoid ulcers and erythema in the cecum5392Extensive ulcers in the ascending and transverse colon
524Male39Mesalazine 3 g/d1104Aphtoid ulcers in the cecum1518Aphtoid ulcers in the cecum
627Female14Azathioprine 2.5 mg/kg per day900Extensive ulcers and erythema proximal to the splenic flexure0Ulcers in the transverse colon
718Male14Azathioprine 2.5 mg/kg per day1690Extensive ulcers and erythema in entire colon2336Ulcers in the cecum, ascending, transverse and descending colon
835Female22Azathioprine 2.5 mg/kg per day314Aphtoid ulcers and erythema in the cecum5392No lesions
932Male22Mesalazine 3 g/d458Extensive ulcers and erythema in entire colon0No lesions
1046Female49Azathioprine 2.5 mg/kg per day393Extensive ulcers and erythema proximal to the splenic flexure0No lesions
1150Female65Azathioprine 2.5 mg/kg per day225Ulcers in the sigmoid8Ulcerative lesions in the splenic flexure;
1239Male62Mesalazine 3 g/d168Aphtoid ulcers in the cecum and ascending colon0No lesions