Observational Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jan 14, 2015; 21(2): 637-643
Published online Jan 14, 2015. doi: 10.3748/wjg.v21.i2.637
Table 1 Study variables
Age< 50 yr of age
≥ 50 yr of age
GenderMale or female
Alarm symptomsAnemia
Hemoglobin level
Male: < 13 g/dL
Female: < 12 g/dL
Weight loss of more than 4 kg
Loss of appetite
Gastrointestinal bleeding
Palpable abdominal mass
Other independent variablesSmoking
Use of NSAID
History of Helicobacter pylori treatment
Table 2 Clinical characteristics of patients stratified by presence and absence of the normal and abnormal endoscopic finding as well as univariable analysis of all corresponding variables
CharacteristicsPercentage of patientsNormalAbnormalP valueUnivariable analysis
OR (95%CI)
Female70.1%53%47%0.3990.7 (0.37-1.47)
Male29.9%45%55%0.7111.02 (0.97-1.56)
Age ≥ 5029%60%40%0.0941.01 (0.99-1.04)
Smoker12%42%58%0.6711.49 (0.56-3.94)
Taking NSAID14%35%65%0.0942.16 (0.86-5.44)
Vomiting18%47%53%0.2851.25 (0.54-2.91)
Prior endoscopy29%38%62%0.0392.06 (1.02-4.13)
Weight loss16%46%54%0.2831.2 5(0.54-2.91)
Loss of appetite16%46%54%0.2831.25 (0.54-2.91)
Dysphagia3%20%80%0.1614.32 (0.47-39.52)
GI bleeding3%20%80%0.1614.32 (0.47-39.52)
Epigastric mass2%0%100%0.075
Low Hb39%41%59%0.2451.08 (0.94-1.25)
Presence of H. pylori22%36%64%0.0442.2 (1.01-4.87)
Table 3 Findings of endoscopy according to American Society for Gastrointestinal Endoscopy guidelines
Endoscopy findingASGE indicatedASGE not indicatedP value
Important endoscopic finding8%3%0.7806