CT colonography in the diagnosis and management of colorectal cancer: Emphasis on pre- and post-surgical evaluation

Table 1 Computed tomographic colonography accuracy for diagnosing synchronous cancers in the colon proximal to an occlusive cancer

	Patients with occlusive cancer	Sensitivity			Specificity
		Target lesions	Per-patient	Per-lesion
Park et al[28]	284	Adenocarcinoma	100% (6/6)	100% (8/8)	87.9 (181/206)
		Advanced neoplasia1	88.6% (39/44)	80% (52/65)
Fenlon et al[35]	29	Adenocarcinoma	100% (2/2)	100% (2/2)	NA
Neri et al[36]	17	Adenocarcinoma	100% (3/3)	100% (3/3)	NA
Coccetta et al[37]	43	Adenocarcinoma	100% (1/1)	100% (1/1)	NA
Galia et al[38]	19	Adenocarcinoma	100% (2/2)	100% (2/2)	NA
Kim et al[39]	67	Adenocarcinoma	100% (3/3)	100% (3/3)	95 (NA)

Data are percentages with the actual numbers of patients and lesions are presented in parentheses.

¹Advanced neoplasia includes both advanced adenomas (≥ 10 mm in size or with a substantial villous component or high-grade dysplasia) and adenocarcinomas. NA: Not available.

Table 2 Computed tomographic colonography accuracy for colonic surveillance after colorectal cancer resection

	Patients		Sensitivity			Specificity
	n	Characteristics	Target lesions1	Per-patient	Per-lesion
Amitai et al[64]	29	Routine surveillance	(Peri) anastomotic recurrence	100% (2/2)	100% (2/2)	NA
			Metachronous polyps	100% (NA)	93% (28/30)	71% (NA)
Fletcher et al[65]	50	Routine surveillance	(Peri) anastomotic recurrence	100% (2/2)	NA	94% (45/48)
			Metachronous polyps ≥ 5 mm	60% (3/5)	NA	84% (38/45)
You et al[67]	80	Suspicion of recurrence	(Peri) anastomotic recurrence	100% (51/51)	100% (51/51)	83% (24/29)
Kim et al[68]	548	Routine surveillance	Metachronous cancer and (peri) anastomotic recurrence	100% (6/6)	100% (7/7)	93.1% (421/452)
			Advanced neoplasia2	81.8% (18/22)	80.8% (21/26)
			All adenomatous lesions3≥ 6 mm	80% (52/65)	78.5% (62/79)

Data are percentages with the actual numbers of patients and lesions are presented in parentheses.

¹Histology and size are not specified unless provided in the original studies;

²Advanced neoplasia includes both advanced adenomas (≥ 10 mm in size or with a substantial villous component or high-grade dysplasia) and adenocarcinomas;

³Both adenomas and adenocarcinomas are included. NA: Not available.