Intra-operative peritoneal lavage for colorectal cancer

Table 1 Demographic and outcome data from studies involved more than 100 patients

Ref.	Patients (n)	Method of IPCC detection	Lavage	Timing of sampling	Yield rate of positive IPCC	Significant impact
						Overall survival	Global recurrence
Noura et al[13]	697	Cyto	100 mL NaCL	Before	2.20%	Yes(5 yr 87% vs 50%)	ND
Nishikawa et al[21]	410	Cyto	200 mL NaCl	Before	7.60%	Yes(5 yr 68% vs 20.6%)	Yes(30% vs 60%)
Fujii et al[15]	293	Cyto	200 mL NaCl	Before	6.00%	NS	NS
Kristensen et al[34]	237	PCR	200-600 mL NaCl	After	8.00%	Yes(median 47 mo vs 22 mo)	ND
Lee et al[16]	234	Cyto	1000 mL NaCl	Before	8.00%	Yes(mean 32 mo vs 25 mo)	ND
Katoh et al[14]	226	Cyto	100 mL NaCl	Before	14.60%	Yes(5 yr 79% vs 14%)	Yes
Yamamoto et al[42]	189	Cyto	50 mL NaCl	Before	5.80%	Yes(5 yr 76% vs 46%)	ND(26% vs 55%)
Temesi et al[23]	145	Cyto		Before	17.00%	ND	ND(23% vs 56%)
Vogel et al[31]	135	ICC	100 mL NaCl	Before	23.00%	Yes(5 yr 85% vs 23%)	ND
Lloyd et al[17]	125	PCR	100 mL NaCl	BeforeAfter	13.00% 20.80%	NS preYes post(mean 88 mo vs 44 mo)	ND(4% vs 22%)
Schott et al[22]	109	ICC	1000 mL NaCl	Before	31.00%	Yes(4 yr 60 mo vs 28 mo)	Yes(47% vs 85%)

Global recurrence range at end of study follow up. IPCC: Intraperitoneal free cancer cells; ND: Not determinable; NS: Not Significant; Cyto: Conventional cytology; PCR: Polymerase chain reaction; ICC: Immunocytochemistry.