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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 28, 2014; 20(44): 16433-16442
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16433
Table 1 Target genes in gastric tumours with microsatellite instability
Gene pathwayTarget gene
DNA repair/chromatin structure regulationATR
BLM
CHK1
MED1
MRE11
MSH2
MSH3
MSH6
RAD50
Signal transductionDP2
IGFIIR
RIZ
TGF-βRII
Transcriptional regulationTCF4
E2F4
microRNA regulationAGO2
TNRC6A
Cell deathAPAF1
BAX
BCL10
CASPASES
FAS
UVRAG
OtherBHD
PAI-1