Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome

Table 1 Summary of polycystic ovary syndrome diagnostic criteria

	Recommended tests	1NIH diagnosis[17]	1Rotterdam diagnosis[18]	Androgen excess polycystic ovary syndrome society[19]
Hyperandrogenism	Clinical: hirsutism, acne, androgenic alopecia	x	x	xx
	Biochemical: elevated total, bioavailable, or free testosterone level
Oligo- or anovulation	Assessment of frequent bleeding intervals < 21 d or infrequent bleeding intervals > 35 d	x	x	x
PCO morphology	Presence of 12 or more follicles 2-9 mm in diameter and/or an increased ovarian volume > 10 mL in either ovary		x	x
Exclusion of other diagnoses2	Thyroid disease (thyroid stimulating hormone)	xx	xx	xx
	Prolactin excess (prolactin)
	Nonclassical congenital adrenal hyperplasia (17-hydroxy progesterone)

¹All criteria require exclusion of other diagnoses. Rotterdam additionally requires 2 of the remaining 3 criteria; NIH criteria do not include PCO morphology for diagnosis; the Androgen Excess Society requires hyperandrogenism with 1 of 2 remaining criteria;

²In select women, may also consider pregnancy, hypothalamic amenorrhea, primary ovarian insufficiency, androgen-secreting tumor, Cushing’s syndrome, acromegaly[103]. NIH: National Institutes of Health; PCO: Polycystic ovary.