PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis

Table 1 Clinical characteristics of subjects with early onset chronic pancreatitis and/or idiopathic recurrent acute pancreatitis

Patient case No.	Sex	Age, in years	Age at symptom onset or diagnosis, in years	Clinical presentation	Mutation
1	Female	45	8	IRAP, pancreatic calcifications at age 15, Puestow procedure at age 22	V39E PRSS1
6	Male	26	20	IRAP, pancreatic calcifications at age 22	N42S PRSS1
8	Female	26	26	IRAP, pancreatic calcifications and dilated main pancreatic duct	N34S SPINK1
15	Male	20	16	IRAP, pancreatic calcifications	V46D SPINK1
19	Male	15	12	Abdominal pain, jaundice, pancreatic calcifications	N34S SPINK1

IRAP: Idiopathic recurrent acute pancreatitis.