Stretta: A valuable endoscopic treatment modality for gastroesophageal reflux disease

Table 1 Putative mechanisms that explain the clinical effectiveness of Stretta

Increased gastric yield pressure

Increased thickness of the lower esophageal sphincter muscle

Decreased gastro-esophageal junction compliance without fibrosis

Decreased transient lower esophageal sphincter relaxations (tLESRs)

Table 2 Key clinical characteristics of Stretta

An outpatient endoscopic option with unique mechanisms of action

Effective, safe and durable

Distinct from medical therapy (pH control, refractoriness)

Distinct from anti-reflux surgery (acid and volume reflux control, side effects)

Not precluding anti-reflux surgery

Repeatable