Diagnosis and evaluation of gastric cancer by positron emission tomography

Table 1 Gastric distention methods in ¹⁸F-fluorodeoxyglucose positron emission tomography and positron emission tomography/computed tomography imaging of gastric cancer

Ref.	Patients	n	Imaging modality	Distention methods	Sensitivity		Specificity
					Before distention	After distention	Before distention	After distention
Tian et al[27]	With suspected gastric tumors	38	FDG PET	Oral intake of vesicant (2-3 g) with 40-60 mL water		83%		88%
Yun et al[26]	After gastrectomy for gastric cancer	30	FDG PET	Drinking at least 300 mL water	94%	88%	69%	92%
Zhu et al[25]	With proven primary gastric carcinomas	3	FDG PET	Intake of 100 g bread and 400 mL cow milk
Zhu et al[20]	With proven gastric tumors	24	FDG PET	Intake of 300-400 mL cow milk		96%
Kamimura et al[21]	With gastric carcinomas	16	FDG PET	Intake 400 mL water	100%	88%	50%	100%
Lee et al[23]	With proven gastric tumors	44	FDG PET/CT	Intake 500 mL water	50%	75%
Ma et al[24]	With suspected gastric tumors	68	FDG PET/CT	Intake milk with diatrizoate meglumine	93%	91%	75%	92%

FDG: ¹⁸F-fluorodeoxyglucose; PET/CT: Positron emission tomography/computed tomography.

Table 2 Comparison of ¹⁸F-FLT and ¹⁸F-fluorodeoxyglucose positron emission tomography or positron emission tomography/computed tomography imaging for detection of gastric cancer

Ref.	Study purpose	Imaging modality	SUV		Sensitivity for detection of primary tumor		Sensitivity for detection of metastasis		Prognostic factor
			18F-FLT	18F-FDG	18F-FLT	18F-FDG	18F-FLT	18F-FDG
Herrmann et al[104]	Preoperative evaluation	PET	Mean: 6.0	Mean: 8.4	100%	69%
Kameyama et al[105]	Preoperative evaluation	PET	Mean: 7.0	9.4	95%	95%
Kameyama et al[103]	Preoperative evaluation	PET	Mean: 2.1-8.0		90%
Ott et al[106]	Neoadjuvant chemotherapy evaluation	PET	Before treatment: 6.1	Before treatment: 8.4					FLT uptake at 2-wk after treatment
			After treatment: 5.3	After treatment: 5.2
Zhou et al[107]	Preoperative evaluation	PET/CT	Max: 5.5	Max: 8.4	92%	95%	Liver: 30%	Liver: 100%
							Bone: 20%	Bone: 100%
							Other organs: 90%-97%	Other organs: 91%-95%

FDG: ¹⁸F-fluorodeoxyglucose; PET/CT: Positron emission tomography/computed tomography; SUV: Standardized uptake value.