Management of post-hepatectomy complications

Table 1 Summary of studies investigating the post-hepatectomy mortality and morbidity

Ref.	Journal	Date of	Country of	NO. of Patients	Disease’s	Mortality and morbidity of hepatectomy
		publication	study	studied	diagnosis
Savage et al[1]	Ann Surg	December 1991	United States	300	Liver trauma or liver tumors	The operative mortality was 19% (1962-1979) or 9.7% (1980-1988), and the overall complication rate was 12.3%
Wu et al[2]	Zhonghua Waike Zazhi	May 2002	China	1762	Liver cancer	The total mortality was 0.40%, and the total complication rate was 4.09%
Ishikawa et al[3]	Hepatogastroenterol	November-December 2002	Japan	139	HCC	The mortality within 30 postoperative days was 2.2%, and complication morbidity was 40.2%
Descottes et al[4]	Surg Endosc	January 2003	France	87	Benign liver tumors	There was no postoperative mortality, and the postoperative complication rate was 5% (laparoscopic liver resection)
Dimick et al[5]	Arch Surg	January 2003	United States	569	Malignant or benign liver disease	The overall in-hospital mortality rate was 4.8%
Benzoni et al[6]	Hepatobiliary Pancreat Dis Int	November 2006	Italy	287	HCC or liver metastasis	In-hospital mortality rate was 4.5%, and the morbidity rate was 47.7%
Benzoni et al[7]	Hepatogastroenterol	January-February 2007	Italy	134	HCC	In-hospital mortality rate was 7.4%, and the morbidity rate was 47.7%
Mullen et al[8]	J Am Coll Surg	May 2007	United States	1059	Noncirrhotic patients	The complication rate was 43%, and the 90-d all-cause mortality rate was 4.7% (1.9% patients died of causes unrelated to the liver)
McKay et al[9]	Ann Surg Oncol	May 2008	Canada	1107	Liver tumor	In-hospital mortality rate was 6.0%, and an overall complication rate was 46%
Feng et al[10]	World J Gastroenterol	December 2008	China	827	Benign hepatic lesion	In-hospital mortality rate was 0.24%, and the postoperative complication rate was 13.54%
Tomuş et al[11]	Chirurgia (Bucur)	May-June 2009	Romania	50	Benign hepatic lesion	There was no mortality, and the morbidity rate was 18%
Cescon et al[12]	Ann Surg	June 2009	Italy	1500	Malignant or benign disease	Overall mortality was 3%, and the morbidity was 22.5%
Huang et al[13]	Chin Med J (Engl)	October 2009	China	2008	Malignant or benign liver disease	The overall hospital mortality was 0.55%, and the overall postoperative complication rate was 14.44%
Mathur et al[14]	J Gastrointest Surg	August 2010	United States	3960	Liver tumor	The overall mortality rate was 2.5%, and the overall complication rate was 23.3%
Sato et al[15]	J Gastroenterol	October 2012	Japan	5270	HCC	In-hospital mortality was 2.6%, and the postoperative complication rate was 14.5%
Dan et al[16]	Chirurgia (Bucur)	November-December 2012	Romania	133	Benign or malignant tumors	The overall mortality rate was 2.25%

HCC: Hepatocellular carcinoma.