HEF-19-induced relaxation of colonic smooth muscles and the underlying mechanisms

Table 1 Effects of HEF-19 on tension and amplitude of spontaneous contraction of descending colonic smooth muscles

Group	After administration (%)
	Tension	Amplitude
Vehicle	97.98 ± 2.37	103.69 ± 10.13
HEF-19 (mol/L)
10-6	89.87 ± 2.60	81.96 ± 13.90a
10-5	75.98 ± 3.2b	48.40 ± 6.07b
10-4	55.05 ± 18.13b	37.77 ± 2.54b

^aP < 0.05,

^bP < 0.01 vs vehicle. Values are mean ± SD, n = 6.