Adenovirus-expressed preS2 antibody inhibits hepatitis B virus infection and hepatic carcinogenesis

doi:10.3748/wjg.v18.i4.349

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2012; 18(4): 349-355
Published online Jan 28, 2012. doi: 10.3748/wjg.v18.i4.349

Table 1 Serum levels of alanine transaminase and aspartate transaminase in hepatitis B virus transgenic mice

Index	Non-virus control(IU/L)	Blank control (DEN)(IU/L)	Ad315(IU/L)	Ad315-preS2Ab(IU/L)
Alanine transaminase	47.2 ± 9.4	300.8 ± 76.4	316.4 ± 41.1	167.2 ± 57.4^a
Aspartate transaminase	118.6 ± 29.5	465.6 ± 156.4	477.4 ± 76.9	239.0 ± 94.7^b

Data are expressed as the mean ± SD for 5 serum samples in every group.

^aP = 0.0141 and

^bP = 0.0243 when comparing the treatment samples to the alanine transaminase and aspartate transaminase levels of the diethylnitrosamine -treated blank control group. DEN: Diethylnitrosamine.

Citation: Zhang Q, Li ZQ, Liu H, Yang JH. Adenovirus-expressed preS2 antibody inhibits hepatitis B virus infection and hepatic carcinogenesis. World J Gastroenterol 2012; 18(4): 349-355
URL: https://www.wjgnet.com/1007-9327/full/v18/i4/349.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i4.349