Lee JE, Kim SW, Kim JS, Choi KY, Kang WK, Oh ST, Yoo IR, Kim SH. Prognostic value of 18-fluorodeoxyglucose positron emission tomography-computed tomography in resectable colorectal cancer. World J Gastroenterol 2012; 18(36): 5072-5077 [PMID: 23049216 DOI: 10.3748/wjg.v18.i36.5072]
Corresponding Author of This Article
Sang Woo Kim, MD, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of South Korea, 505 Banpo-dong, Seocho-gu, Seoul 137-701, South Korea. viper@catholic.ac.kr
Article-Type of This Article
Brief Article
Open-Access Policy of This Article
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World J Gastroenterol. Sep 28, 2012; 18(36): 5072-5077 Published online Sep 28, 2012. doi: 10.3748/wjg.v18.i36.5072
Table 1 Baseline characteristics of the 163 patients
Characteristic
Value
Age (yr), median (range)
60 (30-81)
Male/female, n
98/65
Stage, n
I
23
II
67
III
64
IV
9
Follow-up duration (d), median (range)
756 (419-1355)
Recurrence, n
25
Death, n
3
Table 2 The maximum standardized uptake value and clinicopathologic characteristics
SUVmax < 8.6 (n = 80)
SUVmax≥8.6 (n = 83)
P value
Age (yr), median (range)
61.0 (37-81)
60.0 (30-81)
0.799
Sex (male), n
47
51
0.872
Stage, n
0.346
I
15
8
II
33
34
III
28
36
IV
4
5
Tumor size (cm), median (range)
4.0 (2-13.5)
4.5 (2.4-9.5)
0.02
T stage, n
0.01
1
5
3
2
12
8
3
59
57
4
4
15
N stage, n
0.955
0
47
44
1
17
24
2
16
15
M stage, n
0.562
0
76
78
1
4
5
Histology
0.54
WD
6
7
MD
71
67
PD
4
Mucinous
3
5
Median follow-up (d)
776
756
0.285
Recurrence, n
14
11
0.509
Death, n
2
1
0.547
Table 3 Two-year disease-free survival according to the Kaplan-Meier method
Variable
No. of patients
Two-year DFS (%)
Log-rank P
Age (yr)
0.29
≥ 60
81
90.1
< 60
82
85.4
Sex
0.08
Male
98
83.7
Female
65
93.8
TNM stage
< 0.01
I
23
100
II
67
98.5
III
64
78.1
IV
9
44.4
SUVmax
0.53
≥ 8.6
83
86.7
< 8.6
80
88.8
CEA (ng/mL)
< 0.01
> 5
36
72.2
≤ 5
123
93.5
Table 4 Multivariate Cox regression analysis of disease-free survival
Variable
Relative risk
95% CI
P value
SUVmax ≥ 8.6
0.8
0.35-2.16
0.76
T stage (T3, T4)
3.1
0-6.6
0.94
N stage (N2)
9.78
2.01-49.5
0.01
M stage (M1)
2.51
0.78-7.98
0.12
Age ≥ 60 yr
0.6
0.35-2.16
0.35
Male
1.9
0.71-5.15
0.20
CEA > 5 ng/mL
3.2
1.26-8.42
0.02
Citation: Lee JE, Kim SW, Kim JS, Choi KY, Kang WK, Oh ST, Yoo IR, Kim SH. Prognostic value of 18-fluorodeoxyglucose positron emission tomography-computed tomography in resectable colorectal cancer. World J Gastroenterol 2012; 18(36): 5072-5077