Review
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 7, 2012; 18(33): 4507-4516
Published online Sep 7, 2012. doi: 10.3748/wjg.v18.i33.4507
Table 1 At-risk cohorts for considering surveillance for gastrointestinal malignancies
Esophageal cancer
Barrett’s esophagus
Tylosis palmaris
Lye ingestion
Head and Neck tumors patients with flushing response/inactive ALDH1 allele
Gastric cancer
Hereditary diffuse gastric cancer
Lynch syndrome
Peutz-Jeghers syndrome
Juvenile polyposis syndrome
Li-Fraumeni syndrome
Atrophic gastritis/pernicious anemia
Post-partial gastrectomy
Sporadic adenoma
18-60 yr old Inhabitants of high-risk areas
Pancreatic cancer
Hereditary pancreatitis
Peutz-Jeghers syndrome
Familial pancreatic cancer kindred (≥ 1 first-degree relative and ≥ 3 first, second or third degree relative with pancreatic cancer)
Familial atypical multiple mole melanoma
Familial breast-ovarian cancer
Hereditary nonpolyposis colorectal cancer (Lynch syndrome)
Familial adenomatous polyposis (FAP)
Cystic fibrosis
Fanconi anemia
Ataxia telangiectasia
Incidentally discovered IPMN/PanIN lesions
Hepatocellular carcinoma
Hepatitis B carriers (Asians and Africans)
Hepatitis B cirrhosis
Family history of HCC (mainly Asians and Africans)
Treated hepatitis B cirrhosis (Asians)
Hepatitis C cirrhosis
Treated hepatitis C cirrhosis
Alcoholic cirrhosis
Genetic hemochromatosis
Alfa1-antitrypsin deficiency
Primary biliary cirrhosis
Colorectal cancer
Familial adenomatous polyposis
Attenuated FAP (AFAP)
Hereditary nonpolyposis colorectal cancer (Lynch syndrome)
Peutz-Jeghers syndrome
Juvenile polyposis syndrome
MUTYH-associated polyposis
Hyperplastic polyposis
Patients with long-standing IBD
Acromegaly patients
Positive findings on index colonoscopy (at 50 yr) such as three or more tubular adenomas, tubular adenoma > 10 mm, adenoma with villous histology, adenoma with high-grade dysplasia, after surgical removal of invasive cancer, incomplete removal of neoplastic lesion
IPMN: Intraductal papillary mucinous neoplasms; PanIN: Pancreatic intra-epithelial neoplasia; HCC: Hepatocellular carcinoma; IBD: Inflammatory bowel disease; ALPH1: Aldehyclen dehydrogenase 1; MUTYH: Human MutY homolog.